Abstract:Clinical trials have progressively been providing fundamental support for reducing the uncertainties in decisionmaking in Medicine. Their benefits can be seen historically and are indisputable.Since Lind's celebrated clinical trial in 1753, which demonstrated that scurvy could be treated with citric fruits, this simple and objective study design has improved and continues to improve healthcare as a whole. It suffices to say that before Lind's comparative study, around 50% of the crews of ships involved in long… Show more
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