The comparison of epidemiological characteristics between confirmed and clinically diagnosed cases with COVID-19 during the early epidemic in Wuhan, China

Shi, Fang; Wen, Haoyu; Li, Rui; Bai, Jianjun; Wang, Fang; Mubarik, Sumaira; Liu, Xiaoxue; Yan, Yu; Hong, Qiumian; Cao, Jinhong; Yu, Chuanhua

doi:10.1186/s41256-021-00200-8

Cited by 6 publications

(5 citation statements)

References 25 publications

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“…We identified 9937 potentially relevant records from the literature databases and registers, and 1575 records from the additional searches. After screening the titles, abstracts and full texts, 56 studies (22 cohort studies, 9 case-control studies, and 25 case series) with a total of 79,104 patients were included [ [10] , [11] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] , [54] , [55] , [56] , [57] , [58] , [59] , [60] , [61] , [62] , [63] , [64] , [65] , [66] , [67] , [68] , [69] , [70] , [71] , [72] , [73] , [74] , [75] , [76] ] ( Fig. 1 ).…”

Section: Resultsmentioning

confidence: 99%

“…A total of 26 studies assessed risk factors for death [ 11 , 23 , 24 , 26 , 27 , 29 , 33 , 34 , [37] , [38] , [39] , [40] , [46] , [47] , [48] , 50 , 57 , 58 , 60 , 63 , 68 , 70 , [72] , [73] , [74] , [75] ]. We found low quality evidence that acute kidney injury (AKI, OR =3.15, 95% CI 1.25 to 7.90, two studies) was associated with an elevated risk of death.…”

Section: Resultsmentioning

confidence: 99%

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Risk factors for poor prognosis in children and adolescents with COVID-19: A systematic review and meta-analysis

et al. 2021

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Background This study provides the first systematic review and meta-analysis to identify the predictors of unfavorable prognosis of COVID-19 in children and adolescents. Methods We searched literature databases until July 2021 for studies that investigated risk factors for unfavorable prognosis of children and adolescents with COVID-19. We used random-effects models to estimate the effect size with 95% confidence interval ( CI ). Findings We identified 56 studies comprising 79,104 individuals. Mortality was higher in patients with multisystem inflammatory syndrome (MIS-C) (odds ratio [ OR ]=58.00, 95% CI 6.39–526.79) and who were admitted to intensive care ( OR =12.64, 95% CI 3.42–46.68). Acute respiratry distress syndrme (ARDS) ( OR =29.54, 95% CI 12.69–68.78) and acute kidney injury (AKI) ( OR =55.02, 95% CI 6.26–483.35) increased the odds to be admitted to intensive care; shortness of breath ( OR =16.96, 95% CI 7.66–37.51) increased the need of respiratory support; and neurological diseases ( OR =5.16, 95% CI 2.30–11.60), C-reactive protein (CRP) level ≥80 mg/L ( OR =11.70, 95% CI 4.37–31.37) and D-dimer level ≥0.5ug/mL ( OR =20.40, 95% CI 1.76–236.44) increased the odds of progression to severe or critical disease. Interpretation Congenital heart disease, chronic pulmonary disease, neurological diseases, obesity, MIS-C, shortness of breath, ARDS, AKI, gastrointestinal symptoms, elevated CRP and D-dimer are associated with unfavourable prognosis in children and adolescents with COVID-19.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Risk factors for poor prognosis in children and adolescents with COVID-19: A systematic review and meta-analysis

et al. 2021

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“…This result is in agreement to the findings of Mahmoud et al [10] who estimated the fatality ratio to be 1.40 in Libya in a particular period of time. Shi et al [11] in China reported the risk factors for death were older age, male, severe or critical cases. In Ecuador, Ortiz-Prado et al [12] found the presence of comorbidities, being male and older than 65 years were important determinants of mortality.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of SARS-CoV-2 and Emergence of UK Variant in Zintan City of Libya

Kammon¹,

Giweli²,

Erhouma³

et al. 2021

OJEpi

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Introduction: Coronavirus Disease 2019 (COVID-19) is an infectious respiratory disease caused by SARS-CoV-2. The disease was first broke out in Wuhan City, Hubei Province, China and subsequently spread to all countries and was considered by WHO as a worldwide pandemic. This study is aimed to determine the epidemiology of SARS-CoV-2 and the presence of UK variants in Zintan city of Libya taking some risk factors into account. Methods: In a cross-sectional retrospective study, a total of 15486 nasopharyngeal swabs were collected from COVID-19 suspected patients, travelers and people need disease-free certificates for hospital admission, etc. The samples were collected during the period from August 2020 to June 2021 and tested using real-time RT-PCR (rRT-PCR) kits for SARS-CoV-2 and UK variants. Age groups, sex, and monthly weather were considered as risk factors. Results: The positivity rate of COVID-19 in Zintan city was estimated to be (3891; 25.12%) for the period from August 2020 to June 2021. Females showed significantly (p < 0.05) higher positivity rate (2100; 54%) as compared to males (1791; 46%). Out of the 3891 positive cases, 52 were deceased. The Case Fatality Rate (CFR) was 1.33 recorded significantly in cases aged ≥ 65 years which was higher in males (56.66%) than females (43.33%). The peak of the first wave of infection was recorded in October 2020 (590; 15.15%) whereas the peak of the second wave of infection was recorded in April 2021 (727; 18.71%). The positivity rate was decreased as the temperature increased. UK variant is detected firstly in May 2021 with the percentage of 6.2% of tested samples. Conclusions: Health Authorities are encouraged to continue implementing the control measures during the de-

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“…COVID-19 is a highly contagious respiratory disease with varying symptoms. According to the eighth edition of the COVID-19 Prevention and Control Plan, COVID-19 cases can be divided into mild, moderate, severe, and critical types (13). However, the symptoms at onset are relatively mild, and a significant proportion of patients do not display symptoms prior to the development of respiratory failure.…”

Section: Construction Of the Makeshift Hospitals And Response To Covi...mentioning

confidence: 99%

Medical implementation practice and its medical performance evaluation of a giant makeshift hospital during the COVID-19 pandemic: An innovative model response to a public health emergency in Shanghai, China

Chen

Fan

et al. 2023

Front. Public Health

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IntroductionIn confronting the sudden COVID-19 epidemic, China and other countries have been under great pressure to block virus transmission and reduce fatalities. Converting large-scale public venues into makeshift hospitals is a popular response. This addresses the outbreak and can maintain smooth operation of a country or region's healthcare system during a pandemic. However, large makeshift hospitals, such as the Shanghai New International Expo Center (SNIEC) makeshift hospital, which was one of the largest makeshift hospitals in the world, face two major problems: Effective and precise transfer of patients and heterogeneity of the medical care teams.MethodsTo solve these problems, this study presents the medical practices of the SNIEC makeshift hospital in Shanghai, China. The experiences include constructing two groups, developing a medical management protocol, implementing a multi-dimensional management mode to screen patients, transferring them effectively, and achieving homogeneous quality of medical care. To evaluate the medical practice performance of the SNIEC makeshift hospital, 41,941 infected patients were retrospectively reviewed from March 31 to May 23, 2022. Multivariate logistic regression method and a tree-augmented naive (TAN) Bayesian network mode were used.ResultsWe identified that the three most important variables were chronic disease, age, and type of cabin, with importance values of 0.63, 0.15, and 0.11, respectively. The constructed TAN Bayesian network model had good predictive values; the overall correct rates of the model-training dataset partition and test dataset partition were 99.19 and 99.05%, respectively, and the respective values for the area under the receiver operating characteristic curve were 0.939 and 0.957.ConclusionThe medical practice in the SNIEC makeshift hospital was implemented well, had good medical care performance, and could be copied worldwide as a practical intervention to fight the epidemic in China and other developing countries.

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The comparison of epidemiological characteristics between confirmed and clinically diagnosed cases with COVID-19 during the early epidemic in Wuhan, China

Cited by 6 publications

References 25 publications

Risk factors for poor prognosis in children and adolescents with COVID-19: A systematic review and meta-analysis

Risk factors for poor prognosis in children and adolescents with COVID-19: A systematic review and meta-analysis

Epidemiology of SARS-CoV-2 and Emergence of UK Variant in Zintan City of Libya

Medical implementation practice and its medical performance evaluation of a giant makeshift hospital during the COVID-19 pandemic: An innovative model response to a public health emergency in Shanghai, China

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