The Comparison of Diffusion Weighted Imaging with Other Breast Magnetic Resonance Imaging Parameters in diagnosis of Breast Masses

Abstract

The breast MRI parameters such as morphologic features, enhancement kinetics and diffusion restriction can be used for the differential diagnosis. We aimed to compare the Apperant Diffusion Coefficient (ADC) values of masses with other MRI parameters in diagnosis of breast masses. Between March 2014 and September 2017, 49 female patients in whom a breast mass was diagnosed, determined using ultrasound and mammography and who were further examined with MRI, were enrolled to this study. Total 51 lesions were detected. Routine breast MRI protocol was performed and images were evaluated. The ADC cutoff value was taken as 1,1×10-3 mm 2 /s according to the literature. Fifty-one lesions were diagnosed with biopsy. Of these lesions, 23 (45.1%) were malignant (20 invasive ductal carcinoma and others) and 28 (54.9%) were benign (20 fibroadenomas and others). The accuracy rate of DCE assessment of MRI was 90,9% for benign lesions in with a type 1 curved lesions, and 81,8% for malign lesions in with a type 3 curved lesions. The accuracy rate of ADC values was 93,1% for benign lesions and 95,5% for malign lesions. We believe that the ADC value can provide a higher diagnostic accuracy with the combination of morphological characteristics and contrast kinetics of the lesion and that ADC can be used alone because of its high diagnostic accuracy in some cases.

Diagnostic performance of breast tumor tissue selection in diffusion weighted imaging: A systematic review and meta-analysis

“…The number of malignant and benign lesions ranged from 14-259 and 8-161, respectively, with a mean of 61 malignant and 36 benign lesions per study subset. Seven study subsets were categorized as BTTS1: whole breast tumor tissue selection [35,[38][39][40][41][42][43], 22 as BTTS2: subtracted whole breast tumor tissue selection [15][16][17]20,23,36,37,[44][45][46][47][48][49][50][51][52][53][54][55][56][57][58], 19 as BTTS3: circular breast tumor tissue selection [18,19,21,24,25,36,[59][60][61][62][63][64][65][66][67][68][69][70][71] and 17 as BTTS4: lowest diffusion breast tumor tissue selection…”

“…The vast majority of papers did not mention whether the index test was interpreted without knowledge of the results of the reference standard. Moreover, the ADC threshold was not pre-specified in most papers, with the exception of 8 papers [17,20,44,46,47,54,67,79]. This resulted in a 56% bias risk in domain 2, regarding the Index test.…”