The comparative effectiveness of suction-curettage and onabotulinumtoxin-A injections for the treatment of primary focal axillary hyperhidrosis: A randomized control trial

Ibrahim, Omer; Kakar, Rohit; Bolotin, Diana; Nodzenski, Michael; Disphanurat, Wareeporn; Pace, Natalie; Becker, Lauren; West, Dennis P.; Poon, Emily; Veledar, Emir; Alam, Murad

doi:10.1016/j.jaad.2013.02.013

Cited by 43 publications

(34 citation statements)

References 19 publications

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“…3,4,9 Alternatively, a modified technique can be used, in which 4 or 5 2-mm, evenly spaced, vertically oriented incisions are made using a punch biopsy instrument 1 cm beyond the lateral margin of the axilla, and 4 or 5 similarly sized and spaced incisions are made horizontally 1 cm beyond the inferior margin. 10 LC is performed using a liposuction device and a sharp, rasping-type cannula applied to the dermal-subcutaneous interface. Blunt cannulas may not remove sweat glands as proficiently as cannulas with curettage.…”

Section: Liposuctionmentioning

confidence: 99%

“…3,4,9 Back-and-forth strokes are performed with an upward tension, and the surgeon's thumb and forefinger provide pressure on the skin at either end of the cannula. 4,10 Intraoperative indicators of sufficient LC include a complete elevation of the skin from subcutaneous fat, lividity of the skin, and no fat adhering to the dermis. 9,10 Incisions are closed with either Steri-StripsÔ (3M, St. Paul, MN) or sutures but can be left open for better drainage.…”

Section: Liposuctionmentioning

confidence: 99%

“…4,10 Intraoperative indicators of sufficient LC include a complete elevation of the skin from subcutaneous fat, lividity of the skin, and no fat adhering to the dermis. 9,10 Incisions are closed with either Steri-StripsÔ (3M, St. Paul, MN) or sutures but can be left open for better drainage. A compression bandage for 24 hours or a figure-of-eight dressing for 10 days is applied.…”

Section: Liposuctionmentioning

confidence: 99%

“…4,6,10 The mean HDSS score Local Procedural Approaches for Axillary HH of 3.05 decreased to 2.75 6 months after treatment, which was statistically significant. 10 The aesthetic outcome reported by patients was graded as either very good or good, 4 and 78.4% to 84% of patients were completely satisfied or satisfied with the procedure 3,4,9 ; 94.6% of patients would choose the same procedure again. 3 The relapse rate is approximately 14.5%, and the mean amount of time to return to work was only 1.3 days.…”

Section: Liposuctionmentioning

confidence: 99%

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Local Procedural Approaches for Axillary Hyperhidrosis

Glaser

Galperin

2014

Dermatologic Clinics

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Section: Liposuctionmentioning

confidence: 99%

Section: Liposuctionmentioning

confidence: 99%

Section: Liposuctionmentioning

confidence: 99%

Section: Liposuctionmentioning

confidence: 99%

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Local Procedural Approaches for Axillary Hyperhidrosis

Glaser

Galperin

2014

Dermatologic Clinics

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“…Ibrahim et al55 compared the effectiveness and patient satisfaction of LC versus Btx A injections in 20 axillary HH patients. Toxin injections were randomized to one axillae of each patient and the opposite axillae was treated by LC.…”

Section: Surgerymentioning

confidence: 99%

Management of hyperhidrosis

Stashak¹,

Brewer

2014

CCID

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Primary hyperhidrosis (HH), a condition of sweating in excess of thermoregulatory requirements, affects nearly 3% of the US population and carries significant emotional and psychosocial implications. Unlike secondary HH, primary HH is not associated with an identifiable underlying pathology. Our limited understanding of the precise pathophysiologic mechanism for HH makes its treatment particularly frustrating. However, a wide array of interventions for the treatment of HH have been implemented throughout the world. Herein, we discuss the most extensively studied therapeutic options for primary HH, including systemic oxybutynin, botulinum toxin injections, skin excision, liposuction–curettage, and sympathotomy/sympathectomy. We conclude with a discussion of possible future therapies for HH, including the applications of laser, microwave, and ultrasound technologies.

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Local procedures for axillary hyperhidrosis and osmidrosis: A systematic review of prospective and controlled clinical trials

Grove,

Henning,

Togsverd‐Bo

et al. 2024

JEADV Clinical Practice

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Axillary hyperhidrosis and osmidrosis are challenging to treat, and neither topical nor systemic drugs have provided optimal treatment outcomes. In the past decades, treatment with botulinum toxin (BTX) has gained status as the gold standard, but it has its limitations both in regard to duration as well as indication for osmidrosis, specifically. A variety of local interventions have been explored in both the surgical field and within energy‐based devices (EBDs) for alternative in‐office treatments, but a collective overview is lacking. This study sought to investigate and assess the evidence on and effect of current local procedures for axillary hyperhidrosis and osmidrosis. A systematic search for prospective and controlled clinical trials in the databases PubMed, Embase and Cochrane Library until 31 December 2023 was executed. Relevant literature was identified independently by two authors according to predefined inclusion and exclusion criteria. Fifty‐nine studies met the criteria for final inclusion, of which 46 studies were randomized controlled trials and 13 were nonrandomized trials. The included studies were classified by procedure type. Individually, a total of 28 studies investigated BTXs, 11 studies explored EBDs, while six studies reported on surgical interventions. Additionally, 14 studies evaluated alternative procedures or investigated combinations and side‐by‐side comparisons of the different procedure types. The dominant evidence on efficacy and safety was of BTX A. EBDs are increasingly being investigated with microwave thermolysis appearing to be the singular most established and scientifically well‐founded method. In the surgical field, less‐invasive methods are gaining ground. To meet the increasing demand for individualized treatment, additional high‐quality comparative studies are required for the establishment of a future variety of standard treatments.

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The comparative effectiveness of suction-curettage and onabotulinumtoxin-A injections for the treatment of primary focal axillary hyperhidrosis: A randomized control trial

Cited by 43 publications

References 19 publications

Local Procedural Approaches for Axillary Hyperhidrosis

Local Procedural Approaches for Axillary Hyperhidrosis

Management of hyperhidrosis

Local procedures for axillary hyperhidrosis and osmidrosis: A systematic review of prospective and controlled clinical trials

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