The common bisulfite-conversion-based techniques to analyze DNA methylation in human cancers
Farhad Jeddi,
Elnaz Faghfuri,
Sahar Mehranfar
et al.
Abstract:DNA methylation is an important molecular modification that plays a key role in the expression of cancer genes. Evaluation of epigenetic changes, hypomethylation and hypermethylation, in specific genes are applied for cancer diagnosis. Numerous studies have concentrated on describing DNA methylation patterns as biomarkers for cancer diagnosis monitoring and predicting response to cancer therapy. Various techniques for detecting DNA methylation status in cancers are based on sodium bisulfite treatment. Accordin… Show more
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