Abstract:Commensal protists and gut bacterial communities exhibit complex relationships, mediated at least in part through host immunity. To improve our understanding of this tripartite interplay, we investigated community and functional dynamics between the murine protist Tritrichomonas musculus (T. mu) and intestinal bacteria in healthy and B cell-deficient mice. We identified dramatic, T. mu-dependent remodeling of resident bacterial composition and metabolism in parallel to increases in T. mu metabolism and the exp… Show more
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