2020
DOI: 10.1016/j.ctim.2020.102473
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The combined therapy of a traditional Chinese medicine formula and Western medicine for a critically ill case infected with COVID-19

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Cited by 21 publications
(17 citation statements)
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“…Moreover, the feasibility of the combined use of Chinese and Western medicine has been verified in clinical practice. A 58-year-old severely ill female patient received nonselective antiviral Western medicine treatment (ropinavir/ritonavir, arbidol, and methyl-prednisolone) and also a formula including 16 Chinese medicines based on the patient’s symptoms, which showed the therapeutic effect of TCM on the critical COVID-19 [ 246 ]. The Shanghai Public Health Clinical Center reported four mild or severe cases given antiviral lopinavir/ritonavir and arbidol treatment combined with a Chinese patent medicine Shufeng Jiedu Capsule.…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, the feasibility of the combined use of Chinese and Western medicine has been verified in clinical practice. A 58-year-old severely ill female patient received nonselective antiviral Western medicine treatment (ropinavir/ritonavir, arbidol, and methyl-prednisolone) and also a formula including 16 Chinese medicines based on the patient’s symptoms, which showed the therapeutic effect of TCM on the critical COVID-19 [ 246 ]. The Shanghai Public Health Clinical Center reported four mild or severe cases given antiviral lopinavir/ritonavir and arbidol treatment combined with a Chinese patent medicine Shufeng Jiedu Capsule.…”
Section: Discussionmentioning
confidence: 99%
“…A plentiful of clinical studies and analyses proved that integrated Chinese and Western medicine therapy are much better than pure use of WM for COVID-19 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 . A recent systematic review and meta-analysis of RCTs involving 2275 patients revealed that integration of TCM and WM group was more effective than WM treatment alone in the indicators of clinical cure rate, conversion rate from mild to critical, length of hospital stay, total score of clinical symptoms, symptoms of fever, cough and fatigue, TCM syndrome, negative conversion rate of viral nucleic acid, inflammatory biomarkers of CRP and lung CT without significant difference in adverse effects 81 , 82 .…”
Section: Tcm In the Treatment Of Covid-19mentioning
confidence: 99%
“…In comparison to other recently published studies and protocols recommending natural approaches, the protocol used herein was similar in many ways including use of dietary factors and supplements (e.g., zinc and vitamin D), concurrent use of oral and IV vitamin C, and botanical herbs with immunomodulatory effects. 100 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 Some ways our protocol deviated from what has been published include administration of IV nutrient therapy in an outpatient setting, exclusion of pharmaceutical medications unless indicated for concurrent infection (e.g., CAP), and use of probiotics. IV nutrient therapy in other studies has largely been reserved for patients who are severely ill, in the ICU, and on FiO2; in contrast, IV nutrient therapy was administered preemptively to those with moderate COVID-19 and risk factors for progression to severe disease.…”
Section: Discussionmentioning
confidence: 99%