The combination of traditional and auricular acupuncture to prevent xerostomia and anxiety in irradiated patients with HNSCC: a preventive, parallel, single-blind, 2-arm controlled study

Menezes, Agna Soares da Silva; Sanches, Gabriela Luize Guimarães; Gomes, Emisael Stênio Batista; Soares, Raquel Gusmão; Durães, Cristina Paixão; Fonseca, Larissa Lopes; Filho, Arlen de Paulo Santiago; Ribeiro, Adriana Aparecida Almeida de Aguiar; Nascimento, Jairo Evangelista; Santos, Sérgio Henrique Sousa; Paula, Alfredo Maurício Batista de; Farias, Lucyana Conceição; Guimarães, André Luiz Sena

doi:10.1016/j.oooo.2021.02.016

Cited by 8 publications

(6 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Added to this condition, xerostomia resulting from the use of medications may have favored the manifestation of bruxism, which would play a "protective role" in maintaining airway permeability and also as a way of stimulating salivary flow. 24,27 It should be noted that the auriculotherapy intervention performed in the present case is a non-pharmacological resource already referenced in the literature, which can be used both for the treatment of respiratory and sleep disorders, as well as for bruxism as well to control anxiety and stress, 25,26,28,[29][30][31] which reinforces the fact that it has manifested itself more frequently in moments of patient agitation.…”

Section: Discussionsupporting

confidence: 68%

Auriculotherapy in a patient with Arnold Chiari malformation type II: Case report

Molena

Paulo

Borsatto

et al. 2022

Special Care in Dentistry

View full text Add to dashboard Cite

Aims: Auriculotherapy is a therapeutic method of traditional Chinese Medicine in which a stimulus is exerted on the ear and activates energy channels throughout the body, helping to control anxiety, stress, pain, inflammation, illnesses chronic, and possibly can be used in patient with Arnold Chiari Malformation type II who have painful symptoms that are difficult to resolve. Thus, the aim of this article is to present a case in a patient with Chiari Malformation II where auriculotherapy and effect of laser therapy were performed, to relieve symptoms of agitation, anxiety and healing of self‐mutilation injuries.Case report: Data from medical records were used to collect medical and dental history, complaints and treatments performed. Eight sessions of auriculotherapy and one of laser therapy were carried out in order to heal the lesions. The patient presented lower levels of anxiety, agitation and ceased the habit of self‐mutilation and, consequently, the pain.Conclusions: The use of auriculotherapy led to a considerable improvement in the patient's painful condition and reduced anxiety, also benefiting the interaction with her family members and laser therapy promoted wound healing.

show abstract

Section: Discussionsupporting

confidence: 68%

Auriculotherapy in a patient with Arnold Chiari malformation type II: Case report

Molena

Paulo

Borsatto

et al. 2022

Special Care in Dentistry

View full text Add to dashboard Cite

show abstract

“…Cuando la capacidad secretora residual de las glándulas salivales aún está presente, puede ser apropiada la estimulación de la secreción salival 46 . Entre las opciones reportadas en la literatura están los fármacos parasimpaticomiméticos, la acupuntura, la fitoterapia, la estimulación nerviosa y la PBMT 38,[45][46][47][48][49][50][51][52][53][54][55][56][57][58] .…”

Section: Manejo Terapéutico Para La Xerostomíaunclassified

“…Se cree que los mecanismos por los cuales aumenta la secreción salival son la estimulación del sistema nervioso parasimpático y simpático a través de la activación neuronal y el aumento del flujo sanguíneo en los acinos glandulares 38 . Menezes et al 50 demostraron que el protocolo de acupuntura tradicional y acupuntura auricular redujo los síntomas de xerostomía y aumentó el volumen y densidad salival. Otros estudios evidenciaron que la acupuntura es superior que el cuidado bucal estándar para aliviar los síntomas de xerostomía inducida por radioterapia, presentando una incidencia muy baja de efectos adversos 38,49 .…”

Section: Manejo Terapéutico Para La Xerostomíaunclassified

Manejo odontológico de las manifestaciones orales inducidas por radioterapia de cabeza y cuello

Mejía-Chuquispuma

Flores-Jiménez

Castro-Auqui

et al. 2023

View full text Add to dashboard Cite

La radioterapia es una de las primeras opciones de tratamiento para el cáncer de cabeza y cuello; sin embargo, puede ocasionar diversas manifestaciones secundarias en la cavidad oral tales como mucositis oral, xerostomía, infecciones orales oportunistas, osteorradionecrosis y trismo. El presente artículo tiene como objetivo describir el manejo preventivo y terapéutico de las complicaciones orales inducidas por radioterapia de cabeza y cuello en la práctica odontológica propuestos hasta la actualidad. Se encontraron diversas medidas que han logrado reducir la incidencia y gravedad de dichas manifestaciones orales; sin embargo, aún existen algunas que requieren de más estudios para confirmar su efectividad. Palabras clave: cáncer de cabeza y cuello; manifestaciones bucales; radioterapia; terapéutica.

show abstract

“…A number of randomized and observational studies have found acupuncture can stimulate saliva flow and improve patient-reported outcomes among participants with RIX . These studies were conducted by different investigators, in multiple countries, using different acupuncture points, yet all produced similar positive results.…”

Section: Introductionmentioning

confidence: 99%

“…A number of randomized and observational studies have found acupuncture can stimulate saliva flow and improve patient-reported outcomes among participants with RIX. 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 These studies were conducted by different investigators, in multiple countries, using different acupuncture points, yet all produced similar positive results. One study even demonstrated long-term effects (>3 years) on saliva production, 13 and several studies 14 , 21 , 23 , 24 found that acupuncture can prevent RIX when given concurrently with radiotherapy.…”

Section: Introductionmentioning

confidence: 99%

Acupuncture for Chronic Radiation-Induced Xerostomia in Head and Neck Cancer

Cohen,

Danhauer,

Garcia

et al. 2024

JAMA Netw Open

View full text Add to dashboard Cite

ImportancePatients with head and neck cancer who undergo radiotherapy can develop chronic radiation-induced xerostomia. Prior acupuncture studies were single center and rated as having high risk of bias, making it difficult to know the benefits of acupuncture for treating radiation-induced xerostomia.ObjectiveTo compare true acupuncture (TA), sham acupuncture (SA), and standard oral hygiene (SOH) for treating radiation-induced xerostomia.Design, Setting, and ParticipantsA randomized, blinded, 3-arm, placebo-controlled trial was conducted between July 29, 2013, and June 9, 2021. Data analysis was performed from March 9, 2022, through May 17, 2023. Patients reporting grade 2 or 3 radiation-induced xerostomia 12 months or more postradiotherapy for head and neck cancer were recruited from community-based cancer centers across the US that were part of the Wake Forest National Cancer Institute Community Oncology Research Program Research Base. Participants had received bilateral radiotherapy with no history of xerostomia.InterventionsParticipants received SOH and were randomized to TA, SA, or SOH only. Participants in the TA and SA cohorts were treated 2 times per week for 4 weeks. Those experiencing a minor response received another 4 weeks of treatment.Main Outcomes and MeasuresPatient-reported outcomes for xerostomia (Xerostomia Questionnaire, primary outcome) and quality of life (Functional Assessment of Cancer Therapy–General) were collected at baseline, 4 (primary time point), 8, 12, and 26 weeks. All analyses were intention to treat.ResultsA total of 258 patients (201 men [77.9%]; mean [SD] age, 65.0 [9.16] years), participated from 33 sites across 13 states. Overall, 86 patients were assigned to each study arm. Mean (SD) years from diagnosis was 4.21 (3.74) years, 67.1% (n = 173) had stage IV disease. At week 4, Xerostomia Questionnaire scores revealed significant between-group differences, with lower Xerostomia Questionnaire scores with TA vs SOH (TA: 50.6; SOH: 57.3; difference, −6.67; 95% CI, −11.08 to −2.27; P = .003), and differences between TA and SA (TA: 50.6; SA: 55.0; difference, −4.41; 95% CI, −8.62 to −0.19; P = .04) yet did not reach statistical significance after adjustment for multiple comparisons. There was no significant difference between SA and SOH. Group differences in Functional Assessment of Cancer Therapy–General scores revealed statistically significant group differences at week 4, with higher scores with TA vs SOH (TA: 101.6; SOH: 97.7; difference, 3.91; 95% CI, 1.43-6.38; P = .002) and at week 12, with higher scores with TA vs SA (TA: 102.1; SA: 98.4; difference, 3.64; 95% CI, 1.10-6.18; P = .005) and TA vs SOH (TA: 102.1; SOH: 97.4; difference, 4.61; 95% CI, 1.99-7.23; P = .001).Conclusions and RelevanceThe findings of this trial suggest that TA was more effective in treating chronic radiation-induced xerostomia 1 or more years after the end of radiotherapy than SA or SOH.Trial RegistrationClinicalTrials.gov Identifier: NCT02589938

show abstract

The combination of traditional and auricular acupuncture to prevent xerostomia and anxiety in irradiated patients with HNSCC: a preventive, parallel, single-blind, 2-arm controlled study

Cited by 8 publications

References 48 publications

Auriculotherapy in a patient with Arnold Chiari malformation type II: Case report

Auriculotherapy in a patient with Arnold Chiari malformation type II: Case report

Manejo odontológico de las manifestaciones orales inducidas por radioterapia de cabeza y cuello

Acupuncture for Chronic Radiation-Induced Xerostomia in Head and Neck Cancer

Contact Info

Product

Resources

About