The colon J-pouch as a cause of evacuation disorders after rectal resection: myth or fact?

Rink, Andreas D.; Sgourakis, George; Sotiropoulos, Georgios C.; Lang, Hauke; Vestweber, Karl-Heinz

doi:10.1007/s00423-008-0364-9

Cited by 7 publications

(3 citation statements)

References 82 publications

(117 reference statements)

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“…Therefore, some researchers believe that restoring the volume and compliance of the reconstructed rectum is conducive to improving the shortterm anorectal function of patients with low anterior resection. Clinical researchers have used colon Jpouches or transverse coloplasty pouches to increase the capacity of the reconstructed rectum, but their e cacy is not signi cant (23,24). Preoperative neoadjuvant chemoradiotherapy causes pelvic tissue brosis (25) and damage to the nerve plexus of the pelvic oor, which stiffens the intestinal canal, further reduces peristalsis, worsens postoperative LARS symptoms, prolongs the time for the recovery of anorectal function, and increases complications (26,27).…”

Section: Discussionmentioning

confidence: 99%

A Study on the Clinical Application of Greater Omental Pedicle Flap Transplantation to Correct Anterior Resection Syndrome in Patients With Low Rectal Cancer

Qin

Meng

Huang

et al. 2020

Preprint

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PurposeLow anterior resection syndrome (LARS) is the most common complication after total mesorectal excision (TME) in patients with low rectal cancer and has been a challenge in colorectal surgery that severely impacts the quality of life of patients. This study aimed to introduce a revised surgical procedure which could effectively maintain rectal compliance and significantly improve LARS after the operation.MethodsWe performed mesorectal reconstruction after routine Dixon-TME using greater omental pedicle flap transplantation in 11 patients with low rectal cancer (5 cases of preoperative neoadjuvant chemoradiotherapy, 5 cases of preoperative neoadjuvant chemotherapy, and 1 case of postoperative adjuvant chemotherapy), thereby simulating the initial anatomical structure of the mesorectum and significantly reducing the postoperative anterior resection syndrome. The lars precision syndrome assessment scale (LARSS) was used to access the LARS.ResultsAt 12 weeks after the 11 patients recovered from the anal defecation function, the average score on the LARS questionnaire was 25.5 ± 0.5 (mild). The average time at which anal function began to recover was 6.2 ± 2.6 weeks after surgery. The recovery was rapid, as the rectal and anal function of all patients generally returned to normal levels within 12 weeks, and the quality of life was close to that before surgery. ConclusionGreater omental flap transplantation can significantly improve LARS after Dixon-TME in patients with low rectal cancer.

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Section: Discussionmentioning

confidence: 99%

A Study on the Clinical Application of Greater Omental Pedicle Flap Transplantation to Correct Anterior Resection Syndrome in Patients With Low Rectal Cancer

Qin

Meng

Huang

et al. 2020

Preprint

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“…However, some risks have been identified in multiple, well‐designed studies that are now considered established risks for HCV RFP. These clinical risk factors are outlined in Table .…”

Section: Risks For Hcv‐related Rfpmentioning

confidence: 99%

“…A meta‐analysis by Rink et al. showed that graft survival was improved in HCV patients with steroid‐free regimens. However, others have found no benefit to steroid‐free regimens .…”

Section: Risks For Hcv‐related Rfpmentioning

confidence: 99%

Hepatitis C recurrence: the Achilles heel of liver transplantation

Howell

Angus

Gow

2013

Transplant Infectious Dis

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Hepatitis C virus (HCV) infection is the most common indication for liver transplantation worldwide; however, recurrence post transplant is almost universal and follows an accelerated course. Around 30% of patients develop aggressive HCV recurrence, leading to rapid fibrosis progression (RFP) and culminating in liver failure and either death or retransplantation. Despite many advances in our knowledge of clinical risks for HCV RFP, we are still unable to accurately predict those most at risk of adverse outcomes, and no clear consensus exists on the best approach to management. This review presents a critical overview of clinical factors shown to influence the course of HCV recurrence post transplant, with particular focus on recent data identifying the important role of metabolic factors, such as insulin resistance, in HCV recurrence. Emerging data for genetic markers of HCV recurrence and their usefulness for predicting adverse outcomes will also be explored.

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Chirurgische Therapie des Karzinoms des unteren Rektumdrittels

Rink

2017

coloproctology

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The colon J-pouch as a cause of evacuation disorders after rectal resection: myth or fact?

Abstract: Evacuation disorders are a unique problem of low anterior resection and are not specifically related to the colon J-pouch.

Cited by 7 publications

References 82 publications

A Study on the Clinical Application of Greater Omental Pedicle Flap Transplantation to Correct Anterior Resection Syndrome in Patients With Low Rectal Cancer

A Study on the Clinical Application of Greater Omental Pedicle Flap Transplantation to Correct Anterior Resection Syndrome in Patients With Low Rectal Cancer

Hepatitis C recurrence: the Achilles heel of liver transplantation

Chirurgische Therapie des Karzinoms des unteren Rektumdrittels

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