The “Code Drugs in Cardiac Arrest”—the use of cardioactive medications in cardiac arrest resuscitation

Boyd, Tanner; Brady, William J.

doi:10.1016/j.ajem.2011.04.009

Cited by 9 publications

(6 citation statements)

References 83 publications

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“…Amiodarone is the recommended antiarrhythmic drug in the 2010 Guidelines for Cardiopulmonary Resuscitation. 16 Our study protocol differs significantly from the recommendations such that a low dose of amiodarone was given before defibrillatory shocks together with vasopressin. 16 Our study protocol differs significantly from the recommendations such that a low dose of amiodarone was given before defibrillatory shocks together with vasopressin.…”

Section: Discussionmentioning

confidence: 99%

Resuscitation with amiodarone increases survival after hemorrhage and ventricular fibrillation in pigs

Zoerner

Semenas

2014

Journal of Trauma and Acute Care Surgery

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Section: Discussionmentioning

confidence: 99%

Resuscitation with amiodarone increases survival after hemorrhage and ventricular fibrillation in pigs

Zoerner

Semenas

2014

Journal of Trauma and Acute Care Surgery

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“…There is no evidence to either support or refute the use of lidocaine, and limited evidence credits amiodarone with increased return of spontaneous circulation but no improvement in the rate of discharge. 21 It is sensible to include 2 prefilled syringes of epinephrine in the emergency kit for administration while awaiting EMS. The actual benefit of maintaining amiodarone is dubious.…”

Section: Emergency Kits For the Advanced Providermentioning

confidence: 99%

Emergency Drug Kits: Pharmacological and Technical Considerations

Becker

2014

Anesthesia Progress

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The risk for complications while providing dental procedures is greatest when caring for patients having significant medical compromise. It is comforting that significant adverse events can generally be prevented by careful preoperative assessment, along with attentive intraoperative monitoring and support. Nevertheless, the office team must be prepared to manage untoward events should they arise. This continuing education article will address basic emergency drugs that should be available in all dental practices and additional agents that become essential for those practices providing various levels of procedural sedation or general anesthesia.

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“…Most episodes of sudden cardiac arrest occur in private residences and are unwitnessed; less than 40% receive bystander cardiopulmonary resuscitation (CPR) [ 1 ]. It has been well established that high-quality bystander CPR and early defibrillation for shockable rhythms lead to improved outcomes; despite this, almost 90% of individuals with sudden cardiac arrest will not survive [ 2 , 3 , 4 ]. Rates of survival to hospital discharge have previously been estimated at 9.9–10.4%, with only 8% of patients surviving with a favorable neurologic outcome [ 1 , 2 , 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

“…It has been well established that high-quality bystander CPR and early defibrillation for shockable rhythms lead to improved outcomes; despite this, almost 90% of individuals with sudden cardiac arrest will not survive [ 2 , 3 , 4 ]. Rates of survival to hospital discharge have previously been estimated at 9.9–10.4%, with only 8% of patients surviving with a favorable neurologic outcome [ 1 , 2 , 3 , 4 ]. Survival to hospital discharge is even lower for patients with refractory cardiac arrest, that is, patients requiring CPR for greater than 30 min: approximately 1%, 0.4% with a favorable neurologic outcome [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

A Comparison between Conventional and Extracorporeal Cardiopulmonary Resuscitation in Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis

et al. 2022

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There is limited evidence comparing the use of extracorporeal cardiopulmonary resuscitation (ECPR) to CPR in the management of refractory out-of-hospital cardiac arrest (OHCA). We conducted a systematic review and meta-analysis to compare survival and neurologic outcomes associated with ECPR versus CPR in the management of OHCA. We searched PubMed, EMBASE, and Scopus to identify observational studies and randomized controlled trials comparing ECPR and CPR. We used the Newcastle–Ottawa Scale and Cochrane’s risk-of-bias tool to assess studies’ quality. We used random-effects models to compare outcomes between the pooled populations and moderator analysis to identify sources of heterogeneity and perform subgroup analysis. We identified 2088 articles and included 13, with 18,620 patients with OHCA. A total of 16,701 received CPR and 1919 received ECPR. Compared with CPR, ECPR was associated with higher odds of achieving favorable neurologic outcomes at 3 (OR 5, 95% CI 1.90–13.1, p < 0.01) and 6 months (OR 4.44, 95% CI 2.3–8.5, p < 0.01). We did not find a significant survival benefit or impact on neurologic outcomes at hospital discharge or 1 month following arrest. ECPR is a promising but resource-intensive intervention with the potential to improve long-term outcomes among patients with OHCA.

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The “Code Drugs in Cardiac Arrest”—the use of cardioactive medications in cardiac arrest resuscitation

Cited by 9 publications

References 83 publications

Resuscitation with amiodarone increases survival after hemorrhage and ventricular fibrillation in pigs

Resuscitation with amiodarone increases survival after hemorrhage and ventricular fibrillation in pigs

Emergency Drug Kits: Pharmacological and Technical Considerations

A Comparison between Conventional and Extracorporeal Cardiopulmonary Resuscitation in Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis

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