The Cluster Phenomenon in Patients Who Have Multiple Vertebral Compression Fractures

Kaplan, Frederick S.; Scherl, Jonathan D.; Wisneski, Ronald J.; Cheatle, Martin D.; Haddad, John G.

doi:10.1097/00003086-199312000-00027

Cited by 18 publications

(10 citation statements)

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“…First, decreased bone mineral density is known to be a potential risk factor for pathologic vertebral compression fracture. [25][26][27] Nevertheless, this study did not fully characterize the effects of bone density values. Second, osteoporosis therapies that may play an important role in preventing subsequent adjacent-level fracture were not included in the tested variables.…”

Section: E1228mentioning

confidence: 93%

Sandwich Vertebral Fracture in the Study of Adjacent-level Fracture After Vertebral Cement Augmentation

Wang¹,

Yang²,

Shi³

et al. 2012

Orthopedics

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The literature is inconclusive on the development of adjacent-level vertebral fracture after initial cement augmentation. A preliminary hypotheses is that cement injection exaggerates force transmission to the adjacent vertebral bodies, thereby predisposing those levels to future fractures. A sandwich vertebra is an intact vertebral body located between 2 previously cemented vertebrae. The purpose of this study was to determine whether the risk of adjacent-level fracture increased due to load shift after a cement injection procedure. The authors retrospectively investigated the rate of adjacent-level fracture after sandwiching compared with conservative treatment and determined the potential causative factors of sandwich vertebral fracture. Age, sex, weight, height, body mass index, follow-up period, and location of sandwich level (T10-L2 or nonT10-L2 junction) were assessed. Surgical variables, including surgical procedure (vertebroplasty or balloon kyphoplasty), surgical approach (through uni- or bilateral pedicle), volume of cement injected into the painful vertebrae, cement leakage into the intervertebral disk, cumulative number of treated levels, and pre- and postoperative kyphotic angulation of the sandwich region, were also analyzed. Nine of 42 sandwiched levels developed fatigue fractures, whereas 11 of 71 patients treated with conservative therapy sustained new vertebral fractures adjacent to the treated levels. Only preoperative kyphotic angulation was the variable positively associated with sandwich vertebral fracture at follow-up (P=.021). Although subjected to double load shifts, the sandwich vertebra was not prone to structural failure. Thus, cement augmentation protocol does not increase the incidence of adjacent vertebral fracture.

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Section: E1228mentioning

confidence: 93%

Sandwich Vertebral Fracture in the Study of Adjacent-level Fracture After Vertebral Cement Augmentation

Wang¹,

Yang²,

Shi³

et al. 2012

Orthopedics

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“…Furthermore, the assumption that subsequent VCF rate is temporally linear or that subsequent VCFs are uniformly distributed throughout the spine is probably incorrect. New data support the older clinical observation of spatial and temporal vertebral fracture "clustering" [58]. Recent analysis of pooled data from the combined placebo groups in the prospective Multiple Outcomes of Raloxifene Evaluation and Fracture Prevention Trials suggests that with increasing number and severity of prevalent VCFs the odds ratio for an adjacent, subsequent VCF approaches 6.0 (95% CI 3.4, 10.4) [57].…”

Section: Subsequent Fracturementioning

confidence: 81%

Kyphoplasty and vertebroplasty: How good is the evidence?

McKiernan

2007

Curr Rheumatol Rep

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The absence of Level I evidence undermines the credibility of all clinical studies pertaining to percutaneous vertebral augmentation (ie, kyphoplasty and vertebroplasty). The powerful desire to relieve suffering in the frail elderly cannot substitute for a rigorously designed randomized controlled trial comparing vertebral augmentation with continued nonoperative care. Though the level of available evidence is currently inadequate, its quality is improving.

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“…이 러한 이유로 최근 골다공증성 추체 압박골절에 대해 골시 멘트를 이용한 경피적 추체 성형술이 현재 널리 시행되고 있으며, 이것의 목적은 즉각적인 통증의 완화와 척추의 안 정성을 얻고 부가적으로 추체의 높이와 후만각의 회복 및 유지하는 데 있다고 할 수 있다 2,5,9,13) . 또한 추체 성형술 이후 추체 압박 골절의 발생은 인접된 추체에 밀집되어서 나타나는 경향이 있다고 보고하였으며 9,16,17) , 추체 성형술 부위와 인접 상하 추체 간의 관계에서 추체의 부하 및 형 태에서 의미 있는 변화를 보이는 생역학적 자료들이 보고 되고 있다 3,4,6,19,21) . …”

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The Effect of Adjacent Vertebral Body on Vertebroplasty for Compression Fracture

2010

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Purpose:To analyze the effect of adjacent vertebral body on local sagittal segment in performing vertebroplasty for thoracolumabr vertebral compression fracture on the terms of radiological results. Materials and Methods: We experienced 61 cases of T12 and L1 Compression fracture between June 2003 and November 2005. We classified with 3 groups; no collapse of adjacent body, collapse of adjacent upper body, and collapse of adjacent lower body. The measuring factors were anterior, middle, posterior vertebral height, wedge angle and local kyphotic angle. Results: In group I, Increase rate of anterior, middle, posterior vertebral height and restoration rate of wedge angle, and local kyphotic angle were average of 0.41%, 0.31%, 0.16%, 1.47%, −3.48% respectively. Group II was −3.19%, 0.11%, −3.02%, −1.23%, −4.63%. Group III was −2.28%, 4.72%, −1.01%, −2.41%, −13.12%. There are no significant differences among the groups except local kyphotic angle in Group III statistically. Conclusion:The previous wedged collapse of adjacent vertebral body do not affect local sagittal segment performed vertebroplasty

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The Cluster Phenomenon in Patients Who Have Multiple Vertebral Compression Fractures

Cited by 18 publications

References 0 publications

Sandwich Vertebral Fracture in the Study of Adjacent-level Fracture After Vertebral Cement Augmentation

Sandwich Vertebral Fracture in the Study of Adjacent-level Fracture After Vertebral Cement Augmentation

Kyphoplasty and vertebroplasty: How good is the evidence?

The Effect of Adjacent Vertebral Body on Vertebroplasty for Compression Fracture

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