As they represent an important form of agricultural operation, the sustainable development of family farms is not only an objective necessity for promoting comprehensive rural revitalization in China, but also an imperative strategy for accelerating the construction of agricultural power in China. Based on the survey data of 357 family grain farms in China, this paper uses a structural equation model to empirically analyze the relationship between market-oriented perceptions, organizational resilience, and the sustainable development of family grain farms. The results show that market-oriented perceptions have a significant positive impact on the sustainable development of family grain farms; additionally, organizational resilience plays a mediating role in the impact of market-orientation perceptions on the sustainable development of family grain farms. Based on this, the paper proposes a two-fold approach to the sustainable development of family farms: improving the level of market-orientation perceptions of family farmers and enhancing the organizational resilience of family grain farms.