The Clinicopathological Features of Bladder Carcinoma Among Saudis in Riyadh Central Hospital

Abstract

In a retrospective study, the records of 54 Saudi patients constituting 35.2% of the total number of patients with bladder carcinoma presenting to Riyadh Central Hospital over a seven year period (1985G to 1992G) were reviewed. Eighty-one percent of the patients were habitants of the Central Province of Saudi Arabia. Their mean age was 60 ± 14.8 years. Male to female ratio was 5:1; gross hematuria was the main presenting symptom, occurring in 90% of patients. Twenty-four patients presented six months or more after the onset of symptoms. Upper tract deterioration was noted in 50% of cases at the time of initial presentation. A total of 76.9% of bladder tumors were transitional cell carcinoma, 19.2% were squamous cell carcinoma and 3.8% were poorly differentiated. Only 29% were superficial tumors while 71% were at least muscle-invading at presentation. The majority of tumors were of high grade. This study shows that high grade muscle-invading transitional cell carcinoma is the most frequent histological pattern of bladder tumor in Riyadh Central Hospital. Delay in patient presentation associated with a tendency for invasion of bladder tumor in this region resulted in a high percentage of incurable disease.

Bladder Cancer: Differentiation of Types, Age, Sex Distribution and Associated Variants With Gradation

“…71.5% of bladder cancers in this study were urothelial neoplasms (UNs), followed by squamous neoplasms which accounted for 24.4%. The observed number of urothelial tumors was remarkably similar to the number previously reported from Yemen by Al-Samawi and Aulaqi in 2013 29 and from neighboring Saudi Arabia (77%) 30 . However, lower numbers have been reported in Africa; Nigeria (42%) 31 and Tanzania (28%) 32 .…”

Renal Tumors in Adult Saudi Patients: A Review of 43 Cases

“…These results are compatible with other reports and suggest that there is no delay in the presentation or diagnosis of renal cancer in our patients similar to that seen with other urological cancers in Saudi Arabia. [13][14][15]17 Only 6% of the patients presented in Stage III, a much smaller but variable percentage in comparison to other studies. The incidence of patients with Stage III disease varies greatly in different reports and usually follows the referral pattern to tertiary centers that deal with these patients.…”

Urinary Bladder Cancer in Yemen

“…The observed figure for urothelial neoplasms (78%) was markedly similar with that reported from neighboring Saudi Arabia (77%). 8 However, lower figures have been reported in Africa; Nigeria (42%), 9 and Tanzania (28%). 10 In developed countries, over 90% of the bladder cancer cases are urothelium neoplasms with SCC, adenocarcinoma, and rare types of bladder cancer comprising the remaining 10%.…”