Abstract:Prior studies found high prevalence of respiratory diseases in IgE-deficient patients (IgE<2.5 kU/L). The utility of allergen-specific testing in these patients is unknown. We investigated skin and serum specific IgE (ssIgE) test positivity to environmental allergens in patients with IgE-deficiency. METHODS: IgE-deficient patients with rhinitis and/or asthma diagnoses who had skin prick testing (SPT), intradermal skin testing (IDST) and/or ssIgE done (2010-2018) were randomly matched (age and gender) to three … Show more
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