The Clinical Usefulness of Radionuclide Scintigraphy in Suspected Sacro-Ilitis: A Proospective Study

Chase, Walter F.; Houk, Richard W.; Winn, Richard E.; Hinzman, Gary W.

doi:10.1093/rheumatology/22.2.67

Cited by 18 publications

(6 citation statements)

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“…Bone scintigraphy was frequently used in the past for detecting active sacroiliitis . However, its use has been largely replaced by MRI due to its low sensitivity and specificity .…”

Section: Recommendationsmentioning

confidence: 99%

Clinical practice recommendations for the use of imaging in the diagnosis and management of axial spondyloarthritis in Taiwan

et al. 2019

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Objective: Axial spondyloarthritis (axSpA) is a chronic inflammatory disease bearing challenges in early diagnosis. To improve clinical diagnosis and management of axSpA, recommendations were developed with current axSpA classification criteria and recent advances in medical imaging applications. Methods: A systematic literature review was conducted by 10 rheumatologists and radiologists in Taiwan to retrieve research evidence on the utilization of imaging modalities, including conventional radiography (CR), magnetic resonance imaging (MRI), computed tomography (CT), ultrasound (US), quantitative sacroiliac scintigraphy (QSS), and dual-energy X-ray absorptiometry (DXA). The panel of experts proposed six key issues on the role of imaging in early diagnosis of axSpA, monitoring of disease activity and structural changes, predicting treatment effects, and assessing complications such as osteoporosis and spinal fracture. The consensus was established on the basis of research evidence, clinical experiences and expert opinions. For each | 25 WEI Et al.

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“…Bone scintigraphy was frequently used in the past for detecting active sacroiliitis . However, its use has been largely replaced by MRI due to its low sensitivity and specificity .…”

Section: Recommendationsmentioning

confidence: 99%

Clinical practice recommendations for the use of imaging in the diagnosis and management of axial spondyloarthritis in Taiwan

et al. 2019

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“…Many studies have shown that although highly sensitive to abnormalities of the SI joints, the findings are too nonspecific to consistently diagnose sacroiliitis [20,24]. Correlation with other clinical and radiologic investigations is always necessary.…”

Section: Scintigraphymentioning

confidence: 99%

Imaging in spondyloarthropathies

Grigoryan¹,

Roemer²,

Mohr³

et al. 2004

Curr Rheumatol Rep

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Seronegative spondyloarthropathies comprise a group of inflammatory arthritides, which consists of ankylosing spondylitis, psoriatic arthritis, reactive arthritis (Reiter's syndrome), enteropathic arthritis, and undifferentiated spondyloarthropathy. All of them share common laboratory, clinical, and imaging findings, with characteristic involvement of the sacroiliac joints, spine, and, to various degrees, peripheral joints. For many years, conventional radiography was the mainstay for definitive diagnosis of sacroiliitis and for follow-up of the anatomic changes in the spine, peripheral joints, and entheses. Conventional radiographs remain the imaging investigation of choice; however, they are unable to detect early inflammatory changes of sacroiliitis, which are important for establishing a diagnosis without delay. Other imaging modalities, such as computed tomography, bone scintigraphy, magnetic resonance imaging, and ultrasonography have improved the capabilities of detecting early disease and became useful adjuncts to plain films. In addition, they also have enabled more accurate detection of pathology at various anatomic sites of the musculoskeletal system predominantly involved in spondyloarthropathies. This article will review and highlight the role of each of these modalities in the assessment of the axial and peripheral skeleton in seronegative spondyloarthropathies.

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“…Some of these problems are technical, and relate to the difficulty of isolating the SI joints to obtain proper counts. These problems are amplified when there is increased radiopharmaceutical accumulation in normal surrounding bony sites [20,21]. The use of single photon emission computed tomography (SPECT) has improved three-dimensional localization in and around the SI joints [22].…”

Section: Bone Scintigraphymentioning

confidence: 99%

“…The use of single photon emission computed tomography (SPECT) has improved three-dimensional localization in and around the SI joints [22]. Many studies have demonstrated that although quantitative bone scintigraphy is very sensitive to abnormalities in the SI joints, the findings are too nonspecific to consistently diagnose inflammatory sacroiliitis [18,20,21]. Specifically, one comparison study has shown that sacroiliitis may be diagnosed too frequently in patients who lack clinical and laboratory findings suggestive of sacroiliitis and who turn out to have mechanical causes of lower back pain [23].…”

Section: Bone Scintigraphymentioning

confidence: 99%

Imaging of the seronegative spondyloarthropathies

Luong

Salonen

2000

Curr Rheumatol Rep

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The group of seronegative spondyloarthropathies consists of ankylosing spondylitis, psoriatic arthritis, Reiter's disease, enteropathic spondylitis, and a fifth entity known as undifferentiated spondyloarthropathy. All of these diseases share common clinical and radiographic features with characteristic involvement of the sacroiliac joints, spine, and to various degrees, the peripheral joints. Although plain radiographs are the first line of imaging investigation, they are often insensitive for demonstrating the early changes of sacroiliitis, an important feature for establishing the early diagnosis of seronegative spondyloarthropathy. Other imaging modalities, including conventional tomography, bone scintigraphy, and computed tomography, have improved visualization of inflammatory changes at the sacroiliac joints. This article will review these modalities and emphasize the role of magnetic resonance imaging. By directly imaging changes in the synovium, articular cartilage, and subchondral bone, findings on magnetic resonance imaging are the most sensitive and specific for sacroiliitis and other changes in the axial skeleton. Its role and that of ultrasound in the assessment of the peripheral joints will also be highlighted.

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The Clinical Usefulness of Radionuclide Scintigraphy in Suspected Sacro-Ilitis: A Proospective Study

Cited by 18 publications

References 0 publications

Clinical practice recommendations for the use of imaging in the diagnosis and management of axial spondyloarthritis in Taiwan

Clinical practice recommendations for the use of imaging in the diagnosis and management of axial spondyloarthritis in Taiwan

Imaging in spondyloarthropathies

Imaging of the seronegative spondyloarthropathies

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