“…Neuropathological studies report that about one quarter of autopsied cases of alcohol dependence show evidence of cerebellar pathology (Phillips et al, 1987; Torvik et al, 1982). It is also known from early pneumoencephalographic and more recent CT and MRI studies that cerebellar tissue loss may appear in a significant number of alcohol-dependent subjects (Carlen et al, 1986; Haubek & Lee, 1979; Hillbom, Muuronen, Holme, & Hindmarsh, 1986; Kennedy, Swash, & Wylie, 1976). These neuropathologic and radiologic studies also showed that cerebellar atrophy, or tissue volume loss, or both may be observed in the absence of clinical signs such as ataxia or obvious cognitive impairment.…”