The clinical significance and reliability of self-reported smoking status in patients with intracranial aneurysms: A review

Davis, Matthew C.; Broadwater, Devin R.; Amburgy, John; Harrigan, Mark R.

doi:10.1016/j.clineuro.2015.06.016

Cited by 13 publications

(11 citation statements)

References 71 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…16 Among the many negative consequences of cigarette smoking include that it is a well-known risk factor for the development and rupture of cerebral aneurysms. 4,9,17,21,22,33,34,36,39,43 An estimated 29% of the attributable risk of aneurysmal subarachnoid hemorrhage (SAH) is due to smoking, and smoking cessation decreases the risk of SAH. 21 Although cigarette smoking has decreased internationally, approximately 17.8% of the adult population in the US are current smokers.…”

mentioning

confidence: 99%

Cigarette smoking and outcomes after aneurysmal subarachnoid hemorrhage: a nationwide analysis

Dasenbrock¹,

Rudy²,

Lai³

et al. 2017

Journal of Neurosurgery

View full text Add to dashboard Cite

OBJECTIVE Although cigarette smoking is one of the strongest risk factors for cerebral aneurysm development and rupture, there are limited data evaluating the impact of smoking on outcomes after aneurysmal subarachnoid hemorrhage (SAH). Additionally, two recent studies suggested that nicotine replacement therapy was associated with improved neurological outcomes among smokers who had sustained an SAH compared with smokers who did not receive nicotine. METHODS Patients who underwent endovascular or microsurgical repair of a ruptured cerebral aneurysm were extracted from the Nationwide Inpatient Sample (NIS, 2009-2011) and stratified by cigarette smoking. Multivariable logistic regression analyzed in-hospital mortality, complications, tracheostomy or gastrostomy placement, and discharge to institutional care (a nursing or an extended care facility). Additionally, the composite NIS-SAH outcome measure (based on mortality, tracheostomy or gastrostomy, and discharge disposition) was evaluated, which has been shown to have excellent agreement with a modified Rankin Scale score greater than 3. Covariates included in regression constructs were patient age, sex, race/ethnicity, insurance status, socioeconomic status, comorbidities (including hypertension, drug and alcohol abuse), the NIS-SAH severity scale (previously validated against the Hunt and Hess grade), treatment modality used for aneurysm repair, and hospital characteristics. A sensitivity analysis was performed matching smokers to nonsmokers on age, sex, number of comorbidities, and NIS-SAH severity scale score. RESULTS Among the 5784 admissions evaluated, 37.1% (n = 2148) had a diagnosis of tobacco use, of which 31.1% (n = 1800) were current and 6.0% (n = 348) prior tobacco users. Smokers were significantly younger (mean age 51.4 vs 56.2 years) and had more comorbidities compared with nonsmokers (p < 0.001). There were no significant differences in mortality, total complications, or neurological complications by smoking status. However, compared with nonsmokers, smokers had significantly decreased adjusted odds of tracheostomy or gastrostomy placement (11.9% vs 22.7%, odds ratio [OR] 0.63, 95% confidence interval [CI] 0.51-0.78, p < 0.001), discharge to institutional care (OR 0.71, 95% CI 0.57-0.89, p = 0.002), and a poor outcome (OR 0.65, 95% CI 0.55-0.77, p < 0.001). Similar statistical associations were noted in the matched-pairs sensitivity analysis and in a subgroup of poor-grade patients (the upper quartile of the NIS-SAH severity scale). CONCLUSIONS In this nationwide study, smokers experienced SAH at a younger age and had a greater number of comorbidities compared with nonsmokers, highlighting the negative ramifications of cigarette smoking among patients with cerebral aneurysms. However, smoking was also associated with paradoxical superior outcomes on some measures, and future research to confirm and further understand the basis of this relationship is needed.

show abstract

mentioning

confidence: 99%

Cigarette smoking and outcomes after aneurysmal subarachnoid hemorrhage: a nationwide analysis

Dasenbrock¹,

Rudy²,

Lai³

et al. 2017

Journal of Neurosurgery

View full text Add to dashboard Cite

show abstract

“…Cotinine has a half-life of approximately 16 h compared with nicotine’s 2 h half-life, and therefore, cotinine values are better estimates of present nicotine use in the final hours prior to the serum sampling (Davis et al 2015; Hukkanen et al 2005). To our knowledge, this is the first study of tremor in vibration-exposed workers in which consumption of alcohol, nicotine and caffeine are assessed using biomarkers of exposure rather than by self-report.…”

Section: Discussionmentioning

confidence: 99%

“…Nicotine is mainly metabolized in the liver, and its metabolite cotinine, with a half-life of approximately 16 h (Davis et al 2015), is regarded as the best predictor of total nicotine intake (Davis et al 2015; Hukkanen et al 2005). The plasma concentration of serum carbohydrate-deficient transferrin (sCDT) is increasingly being used as a biomarker of alcohol consumption.…”

Section: Introductionmentioning

confidence: 99%

Tremor and hand-arm vibration syndrome (HAVS) in road maintenance workers

Bast‐Pettersen

Ulvestad

Færden

et al. 2016

Int Arch Occup Environ Health

View full text Add to dashboard Cite

ObjectivesThe aim of this study was to evaluate postural and rest tremor among workers using vibrating hand tools, taking into account the possible effects of toxicants such as alcohol and tobacco. A further aim was to study workers diagnosed with hand-arm vibration syndrome (HAVS) at the time of examination.MethodsThis study comprises 103 road maintenance workers, 55 exposed to vibrating hand tools (age 41.0 years; range 21–62) and 48 referents (age 38.5 years; range 19–64). They were examined with the CATSYS Tremor Pen®. Exposure to vibrating tools and serum biomarkers of alcohol and tobacco consumption were measured.ResultsCumulative exposure to vibrating tools was associated with increased postural (p < 0.01) and rest tremor (p < 0.05) and with a higher Center Frequency of postural tremor (p < 0.01) among smokers and users of smokeless tobacco. Rest tremor Center Frequency was higher than postural tremor frequency (p < 0.001).ConclusionsThe main findings indicate an association between cumulative exposure to hand-held vibrating tools, tremor parameters and consumption of tobacco products. The hand position is important when testing for tremor. Rest tremor had a higher Center Frequency. Postural tremor was more strongly associated with exposure than rest tremor. The finding of increased tremor among the HAVS subjects indicated that tremor might be a part of the clinical picture of a HAVS diagnosis. As with all cross-sectional studies, inferences should be made with caution when drawing conclusions about associations between exposure and possible effects. Future research using longitudinal design is required to validate the findings of the present study.

show abstract

“…A maioria dos casos de HSA se deve à ruptura dos aneurismas intracranianos e, por isso, os fatores de risco para a formação do aneurisma se sobrepõem aos fatores de risco da hemorragia, e consequentemente para o óbito (GUARESI et al, 2011). Sendo a hiperglicemia e instabilidade da pressão arterial e hábitos de vida (tabagismo) os fatores mais importantes e evitáveis para HSA e formação de aneurismas , conhecê-los é fundamental para agir de forma adequada na prevenção primária a fim de reduzir suas taxas de morbimortalidade (SILVA et al, 2014;SINGER et al, 2018;DAVIS et al, 2015). (MOLYNEUX et al, 2002;RAJA et al, 2008).…”

Section: Escala Da Felicidadeunclassified

Perfil Epidemiológico Dos Casos De Tuberculose Notificados No Estado Do Maranhão

Santos¹,

Conceição²,

Conceição³

et al. 2020

Ciências Da Saúde: Campo Promissor Em Pesquisa 2

View full text Add to dashboard Cite

Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição 4.0 Internacional (CC BY 4.0). O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais.

show abstract

The clinical significance and reliability of self-reported smoking status in patients with intracranial aneurysms: A review

Cited by 13 publications

References 71 publications

Cigarette smoking and outcomes after aneurysmal subarachnoid hemorrhage: a nationwide analysis

Cigarette smoking and outcomes after aneurysmal subarachnoid hemorrhage: a nationwide analysis

Tremor and hand-arm vibration syndrome (HAVS) in road maintenance workers

Perfil Epidemiológico Dos Casos De Tuberculose Notificados No Estado Do Maranhão

Contact Info

Product

Resources

About