Abstract:Oince the discovery in the late 1950's of imipramine (Tofranil®), the first tricyclic antidepressant (TCA), and iproniazid, the first monoamine oxidase inhibitor (MAOI), many other TCAs and MAOIs, now being considered the classical antidepressants, have become available. Their effectiveness has been shown in numerous studies, although according to nowadays standards well designed studies (placebo-controlled, defined diagnostic groups, the use of standardized rating scales) with these compounds are relatively s… Show more
“…Waarschijnlijk zijn de 'favoriete' indicatiegebieden iets verschillend, maar de overlap daarvan is in ieder geval bijzonder groot (Birkenha¨ger, Nolen & Moleman, 1992 ; Van den Hoofdakker & Van Berkestijn, 1989 ;Nolen, 1995).…”
“…Waarschijnlijk zijn de 'favoriete' indicatiegebieden iets verschillend, maar de overlap daarvan is in ieder geval bijzonder groot (Birkenha¨ger, Nolen & Moleman, 1992 ; Van den Hoofdakker & Van Berkestijn, 1989 ;Nolen, 1995).…”
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