The Clinical Manifestations of Cardiac Mucormycosis

Jackman, John D.; Simonsen, Randall

doi:10.1378/chest.101.6.1733

Cited by 25 publications

(16 citation statements)

References 14 publications

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“…In another report, two cases of cardiac involvement of zygomycosis were documented to have disseminated zygomycosis as well (7), and all five cases of cardiac zygomycosis had involvement of lungs and other organs in yet another study (12). It has also been reported that the clinical manifestations of cardiac zygomycosis with predominant myocardial involvement are quite nonspecific (7). In the present study, case 1 (20).…”

Section: Discussionsupporting

confidence: 59%

“…Disseminated zygomycosis is a rare, usually fatal infectious complication in immunocompromised patients, and constitutes up to 40% of zygomycosis in patients with hematological malignancy (6) (11). In another report, two cases of cardiac involvement of zygomycosis were documented to have disseminated zygomycosis as well (7), and all five cases of cardiac zygomycosis had involvement of lungs and other organs in yet another study (12). It has also been reported that the clinical manifestations of cardiac zygomycosis with predominant myocardial involvement are quite nonspecific (7).…”

Section: Discussionmentioning

confidence: 99%

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Zygomycosis Presenting as Acute Myocardial Infarction during Hematological Malignancies

et al. 2008

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Section: Discussionsupporting

confidence: 59%

Section: Discussionmentioning

confidence: 99%

Zygomycosis Presenting as Acute Myocardial Infarction during Hematological Malignancies

et al. 2008

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“…Endocarditis leads to valve dysfunction, septic embolism, arrhythmia, and congestive heart failure. Pericardial involvement can produce chest pain and pericardial friction rub (6). Myocardial involvement causing myocardial infarction in renal transplant recipients has been reported previously (12)(13)(14).…”

Section: Discussionmentioning

confidence: 91%

“…Common presentations of mucormycosis are rhinocerebral, pulmonary, cutaneous, gastrointestinal, and disseminated infections . Myocardial involvement of mucormycosis is rarely reported and most commonly occurs in cases of disseminated infection . Here we report the case of a renal transplant recipient with disseminated mucormycosis whose demise was accelerated by the development of a myocardial abscess.…”

mentioning

confidence: 94%

Disseminated mucormycosis with myocardial involvement in a renal transplant recipient

Nam

Jung

Park

et al. 2015

Transplant Infectious Dis

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We report the case of a renal transplant recipient with pulmonary and splenic mucormycosis whose demise was accelerated by a myocardial abscess. Once pulmonary and splenic mucormycosis was diagnosed, liposomal amphotericin B was started and immunosuppressant treatments were discontinued. The pulmonary cavities regressed during treatment, but new myocardial and peri-allograft abscesses developed. The myocardial abscess diffusely infiltrated the left ventricular wall and was associated with akinesia, which led to sudden cardiac arrest. This case demonstrates a rare manifestation of mucormycosis and highlights the fatality and invasiveness of this infection.

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“…Acute myocardial infarction has also been reported due to blockage of major epicardial arteries. There may be endocarditis, myocarditis and pericarditis (16). Left atrium and ventricle are the most common cardiac chambers affected with mural mycotic thrombi.…”

Section: Case Reportmentioning

confidence: 99%