The clinical interview.

Sharp, Katie L.; Williams, Alexander; Rhyner, K; Ilardi, Stephen S.

doi:10.1037/14048-007

Cited by 3 publications

(2 citation statements)

References 55 publications

(78 reference statements)

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“…Women underwent a semistructured clinical interview by a chartered psychologist (C.S.). [16][17][18] The first part of the interview included an evaluation of 12 domains of physical and psychological well-being (Supplementary Appendix 1, https://www.jurology.com). The questions about current anxiety and depression were based on the 2-item GAD-2 which screens for generalized anxiety disorder 19 and the 2-item PHQ-2 screen for depression.…”

Section: Methodsmentioning

confidence: 99%

High Prevalence of Psychological Comorbidities and Functional Neurological Symptoms in Women With Urinary Retention

Selai,

Lee,

Simeoni

et al. 2024

Journal of Urology

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Purpose: Chronic idiopathic urinary retention (CIUR) in young women is poorly understood and a probable etiology is established only in around 40%, most commonly a primary disorder of external urethral sphincter relaxation, sometimes referred to as Fowler's syndrome. A high prevalence of psychological and functional comorbidities is reported, however these have been poorly characterized. Materials and Methods: Women consecutively referred for the assessment and management of CIUR were evaluated cross-sectionally for 13 psychological/ behavioral domains using a structured clinical interview: depression, anxiety, post-traumatic stress disorder (PTSD), other psychiatric history, functional neurological disorder, other functional syndromes, childhood and adult trauma, personality disorder, and self-harm (ever/current). Results: A total of 91 women (mean age [SD]: 34 [11] years) were evaluated. Women with Fowler's syndrome (n [ 69) were younger (mean age [SD]: 32 [9] vs 40 [13] years) than women without Fowler's syndrome and reported shorter mean duration of urinary symptoms (mean [SD]: 5 [6] vs 10 [9]). A high prevalence of psychiatric and psychological comorbidities was reported (97%) including current depression (77%), current anxiety (78%), and PTSD (32%). A high prevalence of functional neurological disorder (56%) and other functional symptoms (65%) was also reported. Self-harm was reported in (14%) and personality disorder in 16%. Childhood trauma was reported in 35% of women. Conclusions: Young women with CIUR report a high burden of psychiatric disorders, affective symptoms, trauma, PTSD, self-harm, and functional neurological disorder, particularly in those with Fowler's syndrome. These factors can undermine the engagement with health care professionals and affect management and should therefore be addressed during the urological assessment.

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Section: Methodsmentioning

confidence: 99%

High Prevalence of Psychological Comorbidities and Functional Neurological Symptoms in Women With Urinary Retention

Selai,

Lee,

Simeoni

et al. 2024

Journal of Urology

View full text Add to dashboard Cite

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“…Empirical evidence supported the reliability of unstructured clinical interviews based on DSM diagnostic criteria for several mental disorders, including substance-related disorders (Miller et al, 2001). Expert psychiatrists conducted a traditional diagnostic assessment (Sharp et al, 2013) based on DSM-5 (American Psychiatric Association, 2013) criteria to assess CoUD. Thirty-five patients were clinically diagnosed as CoUD and included in the study.…”

Section: Participantsmentioning

confidence: 99%

Neurobiological Dysfunctional Substrates for the Self-Medication Hypothesis in Adult Individuals with Attention-Deficit Hyperactivity Disorder and Cocaine Use Disorder: A Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography Study

et al. 2023

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Objectives: Attention-deficit hyperactivity disorder (ADHD) in adulthood shows high co-occurrence rates with cocaine use disorder (CoUD). The self-medication hypothesis (SMH) provides a theoretical explanation for this comorbidity. This study investigates the neurobiological mechanisms that could support SMH in adult patients with attention-deficit hyperactivity disorder with cocaine use disorder (ADHD-CoUD). Materials and Methods: We included 19 age: 32.11 years [7.18]) and 16 CoUD patients (68.7% male; age: 36.63 years [8.12]). All subjects underwent a fluorine-18-fluorodeoxyglucose positron emission tomography ( 18 F-FDG PET) brain scan. We tested brain metabolism differences between ADHD-CoUD and CoUD patients using voxel-based and regions of interest (ROIs)-based analyses. The correlation between dependence/abstinence duration and regional brain metabolism was also assessed in the two groups. Lastly, we investigated the integrity of brain metabolic connectivity of mesocorticolimbic and nigrostriatal dopaminergic systems, and large-scale brain networks involved in ADHD and addictions. Results: The voxel-wise and ROIs-based approaches showed that ADHD-CoUD patients had a lower metabolism in the thalamus and increased metabolism in the amygdala and parahippocampus, bilaterally, than CoUD subjects and healthy controls (HCs). Metabolism in the thalamus negatively correlated with years of dependence in ADHD-CoUD patients. Moreover, connectivity analyses revealed that ADHD-CoUD patients had a more preserved metabolic connectivity than CoUD patients in the dopaminergic networks and large-scale networks involved in self-regulation mechanisms of attention and behaviors (i.e., anterior default mode network [ADMN], executive network [ECN], and anterior salience network [aSAN]). Conclusions: We demonstrated distinct neuropathological substrates underlying substance-use behaviors in ADHD-CoUD and CoUD patients. Furthermore, we provided neurobiological evidence in support of SMH, demonstrating that ADHD-CoUD patients might experience short-term advantages of cocaine assumption (i.e., compensation of dopaminergic deficiency and related cognitive-behavioral deficits).

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The Initial Efficacy of Stand-Alone DBT Skills Training for Treating Impulsivity Among Individuals With Alcohol and Other Substance Use Disorders

et al. 2023

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The clinical interview.

Cited by 3 publications

References 55 publications

High Prevalence of Psychological Comorbidities and Functional Neurological Symptoms in Women With Urinary Retention

High Prevalence of Psychological Comorbidities and Functional Neurological Symptoms in Women With Urinary Retention

Neurobiological Dysfunctional Substrates for the Self-Medication Hypothesis in Adult Individuals with Attention-Deficit Hyperactivity Disorder and Cocaine Use Disorder: A Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography Study

The Initial Efficacy of Stand-Alone DBT Skills Training for Treating Impulsivity Among Individuals With Alcohol and Other Substance Use Disorders

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