The Clinical Implications of Poly Implant Prothèse Breast Implants: An Overview

Wazir, Umar; Kasem, Abdul; Mokbel, Kefah

doi:10.5999/aps.2015.42.1.4

Cited by 21 publications

(15 citation statements)

References 29 publications

(46 reference statements)

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“…11 However, there is no evidence that chronic human exposure to siloxanes with levels found in the rupture condition of PIP implants is carcinogenic. 12 …”

Section: Discussionmentioning

confidence: 99%

Squamous Cell Carcinoma as a Result of Likely Industrial Grade Ruptured Poly Implant Prosthèse Silicone Buttock Implants

Camacho

Obaíd

Bustos

et al. 2020

Aesthetic Surgery Journal Open Forum

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The Poly Implant Prosthèse (PIP) implants were withdrawn from the market in 2010 due to the use of a nonmedical grade silicone filler. In 2012, the French medical authorities and the International Confederation of Societies of Plastic, Reconstructive and Aesthetic Surgery recommended the extraction of PIP implants. However, during the duration of this scandal, each country in the world did not agree with a uniform procedure, and this rule was not implemented in its entirety. Although laboratory test results on PIP implants were negative for cytotoxicity and genotoxicity, there are many reports in the literature of several complications associated with PIP implants, including high rupture rates and the fact that they are 3 to 5 times more likely to produce local tissue reactions. On the other hand, the development of more strange and worse prognosis complications, such as the development of squamous carcinoma associated with the use of silicone implants (not necessarily related to PIP implants), is less known. To date, only 6 cases have been reported, and all are related to breast augmentation. The authors made the first report of primary gluteal squamous cell cancer related to rupture and delayed removal of PIP silicone buttock implants. Level of Evidence: 5

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“…11 However, there is no evidence that chronic human exposure to siloxanes with levels found in the rupture condition of PIP implants is carcinogenic. 12 …”

Section: Discussionmentioning

confidence: 99%

Squamous Cell Carcinoma as a Result of Likely Industrial Grade Ruptured Poly Implant Prosthèse Silicone Buttock Implants

Camacho

Obaíd

Bustos

et al. 2020

Aesthetic Surgery Journal Open Forum

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show abstract

“…Guidelines for the optimal use of ADM are still evolving and are the focus of intense research and training [ 16 ]. Advancements in liposuction techniques that yield a high success rate after autologous fat transplant have led to the development of lipo-modelling techniques as an adjunct in restoring cosmetic defects after breast-conserving surgery and enhancing the cosmetic appearance of a reconstructed breast [ 17 18 19 ].…”

mentioning

confidence: 99%

Evolving Trends in Breast Surgery: Oncoplastic to Onco-Aesthetic Surgery

Carmichael

Mokbel

2016

Arch Plast Surg

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“…5,6 The U.S had not been involved in the PIP crisis, 7 but the European countries and Australia have reacted in different ways to this issue [7][8][9][10] which clinical implications have been reviewed recently. 11 In March 2010, the French national regulation agency (AFFSAPS) requested that doctors' call back all women who had undergone breast reconstruction/augmentation based on PIP implants. The PIP recall was because the implants were produced with a non-homologated silicone gel.…”

mentioning

confidence: 99%

Impact of the Poly Implant Prosthesis Breast Implants Recall in Women With Breast Reconstruction: A South-Eastern French Cross-Sectional Survey Nested in a Prospective Cohort

Julian‐Reynier¹,

Bouhnik²,

Reynier³

et al. 2016

Women Health Open J

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The Poly Implant Prosthesis (PIP) Breast Implants crisis involved thousands of women in the countries concerned, women with breast cancer in particular. It was proposed here to investigate the impact of the PIP Breast Implants recall on women who had undergone Breast Reconstruction at the time of the recall and to analyze the determinants of their Breast Reconstruction decisional outcomes. A cross-sectional telephone survey was performed nested in prospective geographically based cohorts, which consisted of women from the southeastern France with breast cancer. Women were selected who had Breast Reconstructive surgery just before the PIP recall occurred. Dependent variables were the Psychological Impact of the event, Decisional Regret, and Satisfaction with Breast Reconstruction. Determinants of regret and satisfaction were analyzed using simultaneous equations. Among the 148 eligible women, 113(76%) participated. At the initial reconstruction, 90% (n=102) had a Breast Implant, 10% (n=11) had an autologous reconstruction. The PIP recall induced less intrusive thoughts, measured with the Impact of the Event Scale, in the non-PIP groups compared to the PIP one (p=0.025). Regrets about Breast Reconstruction were expressed by 57%; they occurred more frequently when the decision-making was not felt to be sufficiently proactive (adjusted Odds Ratio (ORadj) 5.1; 95% Confidence Interval (CI) (1.2-20.9)) and in those who were dissatisfied with their Breast Reconstruction (ORadj 0.7(95% CI (0.5-0.9))). Satisfaction was significantly lower in women with a Breast Implant, those whose trust in doctors had decreased, in the information-seekers and in less health-literate women. The PIP recall was not found to affect intrusive ideas or denial in women who did not have a PIP Breast Reconstruction. The high frequency of regrets could be reduced by involving women more strongly in the initial decision-making process. Using existing data-bases to assess the impact of new devices on patients' health is an option which organization deserves to be discussed.

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The Clinical Implications of Poly Implant Prothèse Breast Implants: An Overview

Cited by 21 publications

References 29 publications

Squamous Cell Carcinoma as a Result of Likely Industrial Grade Ruptured Poly Implant Prosthèse Silicone Buttock Implants

Squamous Cell Carcinoma as a Result of Likely Industrial Grade Ruptured Poly Implant Prosthèse Silicone Buttock Implants

Evolving Trends in Breast Surgery: Oncoplastic to Onco-Aesthetic Surgery

Impact of the Poly Implant Prosthesis Breast Implants Recall in Women With Breast Reconstruction: A South-Eastern French Cross-Sectional Survey Nested in a Prospective Cohort

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