“…She subsequently developed three further tumours on the right side weighing 991 g, 451 g, and 6 g. These consisted of neurofibroma, neurilemmoma, and frank fibrosarcoma in the largest tumour (Parish, 1957). Obvious symptoms of malignant spread to the glands in the neck and to subcutaneous sites occurred in one patient, and general symptoms of the onset of malignancy, for example anaemia and loss of weight, occurred in others.…”