The clinical efficacy and experience of bipedicular percutaneous vertebroplasty combined with postural reduction in the treatment of Kümmell’s disease

Jiang, Jiang; Gu, Fulong; Li, Zhongwei; Zhou, Yi Dan

doi:10.1186/s12891-020-3113-z

Cited by 21 publications

(28 citation statements)

References 19 publications

(19 reference statements)

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“…After filling the fissures in the vertebral body with bone cement, the height and kyphosis deformity of the vertebral body were partially restored and corrected, and the abnormal activity of the injuried vertebral body was eliminated, which was an important reason for pain relief [11]. Previous studies have found that both PVP and PKP can effectively relieve the lower back pain of Kümmell's disease, achieve satisfactory clinical effect, and at the same time partially restore the height of the vertebra and correct the kyphosis [11,[21][22][23][24][25][26][27][28]. During spinal flexion and extension, due to the presence of IVC and the formation of false joints, the injured vertebra of Kümmell's disease can stretch and expand, which can widen the fractured vertebra.…”

Section: Discussionmentioning

confidence: 99%

Comparison of the clinical outcomes of percutaneous vertebroplasty vs. kyphoplasty for the treatment of osteoporotic Kümmell’s disease:a prospective cohort study

Chang¹,

Bei

Shu³

et al. 2020

Preprint

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Background Percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) are widely used in the treatment of Kümmell's disease. The purpose of this article is to investigate the clinical efficacy of PVP and PKP for Kümmell's disease. Methods The clinical data that 56 cases of OVCF treated with either PVP (28 cases) or PKP (28 cases) and met the selection criteria from December 2015 to December 2017 were prospectively analyzed. Gender, age, course of disease, injury segment, BMD, VAS, ODI, imaging measurement indexes before surgery between the two groups showed no significant difference (all P>0.05). The bone cement leakage rate, bone cement injection amount, operation time, VAS, ODI, the rate of vertebral compression, correction rate of kyphosis and refracture rate of adjacent vertebra in 2 years were compared between the two groups to calculate clinical efficacy. Results The two groups were followed up for 24-48 months. There was no significant difference in the follow-up time, amount of bone cement injected, incidence of bone cement leakage and refracture rate of adjacent vertebra between the two groups (all P > 0.05). The operation time, intraoperative blood loss and fluoroscopy times of the PVP group were significantly lower than those of the PKP group (all P = 0.000). VAS score and ODI of the two groups were significantly lower at 1 d, 1 year and 2 years after surgery than before surgery (all P <0.05), but there was not statistically significant difference between the two groups at each time point after surgery (all P> 0.05). The rate of vertebral compression and kyphosis correction in the two groups were significantly corrected (P <0.05, respectively) and decreased significantly with time (all P <0.05), But there was not significant difference between the two groups at any time point (all P> 0.05). Conclusion Both PVP and PKP can achieve similar effects in the treatment of Kümmell's disease. Because the cost, operation time, blood loss, radiation exposure and surgical procedure of PVP are less than those of PKP, PVP has more clinical priority value.

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Section: Discussionmentioning

confidence: 99%

Comparison of the clinical outcomes of percutaneous vertebroplasty vs. kyphoplasty for the treatment of osteoporotic Kümmell’s disease:a prospective cohort study

Chang¹,

Bei

Shu³

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…After filling the fissures in the vertebral body with bone cement, the height and kyphosis deformity of the vertebral body were partially restored and corrected, and the abnormal activity of the injuried vertebral body was eliminated, which was an important reason for pain relief [11]. Previous studies have found that both PVP and PKP can effectively relieve the lower back pain of Kümmell's disease, achieve satisfactory clinical effect, and partially restore the height of the vertebra and correct the kyphosis [11,[22][23][24][25][26][27][28][29]. During spinal flexion and extension, due to the presence of IVC and the formation of pseudojoint, the injured vertebra of Kümmell's disease can stretch and expand, which can widen the fractured vertebral body.…”

Section: Discussionmentioning

confidence: 99%

“…And the following indexes were calculated. 1) Rate of vertebral compression = the height of the injured vertebral body / the average height of adjacent upper and lower vertebral body heights [10]; 2) Correction degree of kyphosis = (preoperative kyphosis angle -postoperative kyphosis angle) / preoperative kyphosis angle × % [11].…”

Section: Outcome Measurementmentioning

confidence: 99%

Comparison of the clinical outcomes of percutaneous vertebroplasty vs. kyphoplasty for the treatment of osteoporotic Kümmell’s disease:a prospective cohort study

Chang

Bei²,

Shu

et al. 2020

BMC Musculoskelet Disord

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Background: Percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) are widely used in the treatment of Kümmell's disease. The purpose of this article is to investigate the clinical efficacy of PVP and PKP for Kümmell's disease. Methods: The clinical data that 56 cases of Kümmell's disease treated with either PVP (28 cases) or PKP (28 cases) from December 2015 to December 2017 were prospectively analyzed. Gender, age, course of disease, injury segment, bone mineral density (BMD), visual analogue scale (VAS), Oswestry disability index (ODI), imaging measurement indexes before surgery between the two groups showed no significant difference (all P > 0.05). The bone cement leakage rate, bone cement injection amount, operation time, VAS, ODI, the rate of vertebral compression, correction rate of kyphosis and refracture rate of adjacent vertebra in 2 years were compared between the two groups to calculate clinical efficacy. Results: The two groups were followed up for 24-48 months. There was no significant difference in the follow-up time, amount of bone cement injected, incidence of bone cement leakage and refracture rate of adjacent vertebrae between the two groups (all P > 0.05). The operation time, intraoperative blood loss and fluoroscopy times of the PVP group were significantly lower than those of the PKP group (all P = 0.000). VAS score and ODI of the two groups were significantly lower at 1 day, 1 year and 2 years after surgery than before surgery (all P < 0.05), but there was not statistically significant difference between the two groups at each time point after surgery (all P > 0.05). The rate of vertebral compression and kyphosis correction in the two groups were significantly corrected (P < 0.05, respectively) and decreased significantly with time (all P < 0.05), But there was not significant difference between the two groups at any time point (all P > 0.05).

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“…After the ssures of the fractured vertebral body lled with bone cement, the abnormal activity of the vertebral body was eliminated and the fractured vertebrae was stabilized, which was an important reason for pain relief [16]. Besides, the height of the vertebral body was partially restored and kyphosis deformity was partially corrected [16][17][18][19][20][21][22][23][24]. The ODI and VAS after PVP surgery both in Kümmell's disease and OVCFs groups were signi cantly decreased, but the mean scores were higher in the Kümmell's disease group than in the OVCFs groups [25].…”

Section: Resultsmentioning

confidence: 99%

“…Kümmell's disease is a chronic, non-healing osteoporotic vertebral compression fractures (OVCFs), which is associated with the ischemic necrosis of vertebral body after fracture and vertebral pseudarthrosis [1,2]. Due to the continuous collapse of vertebral body after minor trauma, clinical manifestations are often intractable low back pain, and even the symptoms of spinal nerve function damage [3].…”

Section: Introductionmentioning

confidence: 99%

Comparison of the clinical manifestations and cement distribution after percutaneous vertebroplasty between thoracolumbar Kümmell’s disease and OVCFs

Wang¹,

Chen

2020

Preprint

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Background：Kümmell's disease is a chronic, non-healing osteoporotic vertebral compression fractures (OVCFs), which is associated with ischemic necrosis and vertebral pseudarthrosis. The purpose of this study was to compare the therapeutic effect and distribution characteristics of bone cement in the percutaneous vertebroplasty (PVP) treatment between thoracolumbar Kümmell's diseases and OVCFs.Methods: A total of 70 patients with Kümmell ’s disease (K group) or OVCFs (O group) who underwent PVP surgery from February 2016 to February 2018 were included in this study. The follow-up time was 24-48 months. The course of disease was significantly longer in the K group than in the O group (P=0.000). Most cases in the K group had no history of trauma, while most cases in the O group had a history of falls (P=0.001). The vertebral compression rate and degree of osteoporosis were more serious in the K group than in the O group (P<0.05, respectively). Distribution pattern, volume and leakage rate of bone cement, operation time, VAS score, ODI, correction rates of vertebral compression and kyphosis, re-fracture rate of adjacent vertebrae between the two groups were compared to assess clinical effect.Results: The amount of bone cement injected was significantly higher in the K group than in the O group (P=0.025). The cement distribution pattern of local solid lump was dominant in the K group (65.71%), while intercalation with trabeculae was dominant in the O group (74.29%) (P<0.001). VAS and ODI were significantly lower both in the two groups at the 1st day, 1st year and 2nd years after surgery than before surgery (all P<0.05), but significantly lower in the K group than in the O group at each time point after surgery (all P<0.05). The correction rates of kyphosis and vertebral compression in both groups were significantly improved (P<0.05, respectively) and gradually lost with time (P<0.05, respectively). The correction rates of kyphosis and vertebral compression were significantly higher in the K group than in the O group at each time point after surgery (all P<0.05).Conclusion: Kümmell's disease has a higher degree of disease progression and osteoporosis than OVCFs. PVP can better restore partial vertebral height and correct kyphosis in the treatment of Kümmell's disease, while can better alleviate pain and improve ODI in the treatment of OVCFs.

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The clinical efficacy and experience of bipedicular percutaneous vertebroplasty combined with postural reduction in the treatment of Kümmell’s disease

Cited by 21 publications

References 19 publications

Comparison of the clinical outcomes of percutaneous vertebroplasty vs. kyphoplasty for the treatment of osteoporotic Kümmell’s disease:a prospective cohort study

Comparison of the clinical outcomes of percutaneous vertebroplasty vs. kyphoplasty for the treatment of osteoporotic Kümmell’s disease:a prospective cohort study

Comparison of the clinical outcomes of percutaneous vertebroplasty vs. kyphoplasty for the treatment of osteoporotic Kümmell’s disease:a prospective cohort study

Comparison of the clinical manifestations and cement distribution after percutaneous vertebroplasty between thoracolumbar Kümmell’s disease and OVCFs

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