The clinical effect of modified slow Mohs circular skin biopsy on penoscrotal extramammary Paget's disease

Song, Chuan-Gui; Li, Junhua; Luo, Xiaobin; Zhou, Peng; Yang, Longfei; Peng, Jian-Zhong

doi:10.1016/j.asjsur.2023.01.079

Cited by 2 publications

(1 citation statement)

References 16 publications

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“…A systematic review and meta-analysis demonstrated a 7.3% local recurrence rate after MMS compared to 26.3% after WLE [7]. Although regular MMS led to complete clearance of EMPD in this case, modified slow MMS may provide better clinical outcomes [8,9]. Adjuvant immunotherapy with topical imiquimod 5%, brachytherapy, photodynamic therapy, or external beam radiotherapy may decrease the risk of EMPD recurrence following definitive surgical therapy [10].…”

Section: Discussionmentioning

confidence: 93%

Primary Extramammary Paget’s Disease Following Previously Treated Secondary Extramammary Paget’s Disease Over the Scrotum: A Rare Case Successfully Treated With Mohs Micrographic Surgery

Verma,

Ahmad,

Friedmann

et al. 2024

Cureus

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Section: Discussionmentioning

confidence: 93%

Primary Extramammary Paget’s Disease Following Previously Treated Secondary Extramammary Paget’s Disease Over the Scrotum: A Rare Case Successfully Treated With Mohs Micrographic Surgery

Verma,

Ahmad,

Friedmann

et al. 2024

Cureus

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Superficial circumflex iliac artery perforator propeller flap for penoscrotal extramammary Paget's disease

Dong,

Xiao,

Wang

et al. 2024

Int J Dermatology

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BackgroundExtramammary Paget's disease (EMPD) is a rare intra‐epidermal adenocarcinoma, and reconstruction of the penoscrotal region remains a clinical challenge. The superficial circumflex iliac artery perforator (SCIP) flap has been successfully used as a free flap, while its application as a propeller flap in the reconstruction of penoscrotal EMPD defect is rarely reported. The objective was to evaluate the safety and efficacy of the SCIP propeller flap in the reconstruction of penoscrotal defects in EMPD.MethodsBetween September 2010 and August 2022, consecutive patients diagnosed with penoscrotal EMPD were enrolled. All patients underwent penoscrotal EMPD excision and reconstruction with SCIP propeller flap combined with other flaps or skin grafts on individual defects. Demographic information, surgical parameters, postoperative complications, patient satisfaction, and recurrence rates were analyzed.ResultsTwenty‐four patients (mean age, 73 ± 8.8 years; mean BMI, 23.98 ± 3.62 kg/m2) with 33 SCIP propeller flaps (mean size 120.1 cm2; range, 24–208 cm2) were included, and the mean defect size was 67.4 cm2 (range, 12–255 cm2). The mean operative duration was 385.4 ± 146.8 min. Fifteen patients received autologous full‐thickness skin grafts, and four received other flaps simultaneously. All flaps survived without total or partial loss, and all donor sites achieved primary closure, though local hematoma (one case) and limited skin graft necrosis (two cases) were observed. All patients experienced complete wound healing and maintained penoscrotal morphology and function without recurrent lesions over a mean follow‐up of 59 months.ConclusionsThe SCIP propeller flap seems a safe and effective reconstructive method for penoscrotal EMPD.Level of evidenceIV.

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The clinical effect of modified slow Mohs circular skin biopsy on penoscrotal extramammary Paget's disease

Cited by 2 publications

References 16 publications

Primary Extramammary Paget’s Disease Following Previously Treated Secondary Extramammary Paget’s Disease Over the Scrotum: A Rare Case Successfully Treated With Mohs Micrographic Surgery

Primary Extramammary Paget’s Disease Following Previously Treated Secondary Extramammary Paget’s Disease Over the Scrotum: A Rare Case Successfully Treated With Mohs Micrographic Surgery

Superficial circumflex iliac artery perforator propeller flap for penoscrotal extramammary Paget's disease

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