The Clinical Differentiation of Bacterial and Fungal Keratitis: A Photographic Survey

Dalmon, Cyril A; Porco, Travis C.; Lietman, Thomas M.; Prajna, Namperumalsamy Venkatesh; Lalitha, Prajna; Das, Mano Ranjan; Kumar, Jayant; Mascarenhas, Jeena; Margolis, Todd P.; Whitcher, John P.; Jeng, Bennie H.; Keenan, Jeremy D.; Chan, Matilda F.; McLeod, Stephen D.; Acharya, Nisha R.

doi:10.1167/iovs.11-8478

Cited by 128 publications

(119 citation statements)

References 21 publications

Supporting

Mentioning

104

Contrasting

Unclassified

Order By: Relevance

“…Gram-positive cocci typically presented round or oval ulceration with distinct borders and superficial stromal haze. 8,9 Because keratitis due to GPC share similar corneal finding and is commonly reported microbes, it is difficult to suspect P. acnes as causative organism based entirely on slit-lamp examination. But presence of dense stromal infiltration suggests infection associated with P. acnes.…”

Section: Discussionmentioning

confidence: 99%

Clinical Features of Infectious Keratitis Caused by Propionibacterium Acnes

Lim

Joo

2017

Eye &Amp; Contact Lens: Science &Amp; Clinical Practice

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Clinical Features of Infectious Keratitis Caused by Propionibacterium Acnes

Lim

Joo

2017

Eye &Amp; Contact Lens: Science &Amp; Clinical Practice

View full text Add to dashboard Cite

show abstract

“…6,7 Acanthamoeba keratitis is associated with epithelial/subepithelial infiltrate, punctate keratopathy, development of a late ring infiltrate, salt-like dense infiltrates, and groove-shaped corneal melting.- [7][8][9] Despite these clues, the ability of an ophthalmologist to predict the etiology of an ulcer based on its appearance is far from perfect. 7,10 Both the incidence and etiology of infectious keratitis varies by geographic locale. For example, the incidence of microbial keratitis in the United States is 11.0-27.6 per 100,000 years.…”

Section: Introductionmentioning

confidence: 99%

Geographic Disparities in the Etiology of Bacterial and Fungal Keratitis in the United States of America

Estopinal

Ewald

2016

Seminars in Ophthalmology

View full text Add to dashboard Cite

Infectious keratitis is a serious cause of vision loss. Proper treatment of infectious keratitis requires antimicrobials that target the organism responsible for a patient's ulcer. The frequency of infection by a given organism varies by location. We examined the literature to determine geographic disparities in the etiology of bacterial and fungal keratitis in the United States of America. Bacterial keratitis makes up a greater proportion of cases in northern locations, and fungal keratitis increases in prevalence in southern locations. Gram-negative organisms make up a greater proportion of bacterial keratitis in southern locations when compared to northern locations.

show abstract

“…Clinical features of FK are the same as those of other microbial infections ( Figure 1) and must be differentiated from bacterial, herpetic, and acanthamoeba keratitis (21). Only serrated margins and raised slough were independently associated with FK (22) and exudates presented more frequently in cases suffering from filamentous FK, hypopyon, and fibrinous than in bacterial keratitis (22).…”

Section: Signs and Symptomsmentioning

confidence: 92%

Management of Fungal Keratitis in Pediatric Patients

Badiee

Nejabat

Choopanizadeh

2017

Arch Pediatr Infect Dis

View full text Add to dashboard Cite

Context: Fungal keratitis is an uncommon infection with high morbidity in pediatric patients. Trauma is the most common risk factor for infection in children. Thus, rapid diagnosis should be made by scoring clinical features and mycological examination. This review discusses the management of fungal keratitis in pediatric patients. Evidence Acquisition: In this narrative review, the most recently published data on pediatric fungal keratitis, respective prominent signs and symptoms, etiologic agents, diagnosis and treatment of this infection have been reviewed. Results: Laboratory methods such as investigation of smear by potassium hydroxide and staining and cultural and molecular methods can be helpful in the diagnosis. Treatment of this infection with improved outcome is challenging. Medical therapy (topical and systemic treatments) is the first choice of treatment, but early surgical intervention and removal of the infected tissues are critical for effective cure. Lack of response to these therapies requires corneal transplantation. Unfortunately, loss of useful vision rate was found in patients even with treatment by antifungal agents. Conclusions:The signs and symptoms of fungal keratitis are similar to those of other microbial keratitis. Use of diagnostic methods and early treatment are helpful for recovery in infected pediatric patients.

show abstract

The Clinical Differentiation of Bacterial and Fungal Keratitis: A Photographic Survey

Cited by 128 publications

References 21 publications

Clinical Features of Infectious Keratitis Caused by Propionibacterium Acnes

Clinical Features of Infectious Keratitis Caused by Propionibacterium Acnes

Geographic Disparities in the Etiology of Bacterial and Fungal Keratitis in the United States of America

Management of Fungal Keratitis in Pediatric Patients

Contact Info

Product

Resources

About