The clinical course of alcohol-related problems in alcohol dependent and nonalcohol dependent drinking women and men.

Schuckit, Marc A.; Daeppen, Jean Bernard; Tipp, Jayson E.; Hesselbrock, Michie N.; Bucholz, Kathleen K.

doi:10.15288/jsa.1998.59.581

Cited by 131 publications

(103 citation statements)

References 33 publications

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“…The problems included in the list of 44 major life events relating to alcohol have been described in more detail in another publication (Schuckit et al, 1998a). Only current smokers were more likely than the remaining groups to have ever been treated for alcoholism.…”

Section: Resultsmentioning

confidence: 99%

“…For example, there are gender differences in the clinical course of alcohol and nicotine dependence (Carmody et al, 1985;Breslau et al, 1994;Patton et al, 1998b;Schuckit et al, 1998a), raising the question of whether the correlates of conjoint alcoholism and heavy smoking apply equally to men and women. A second potentially confounding factor is the possibility that the more severe clinical course of conjoint alcohol and nicotine dependence might reflect the impact of a third disorder.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical Correlates of Cigarette Smoking and Nicotine Dependence in Alcohol-Dependent Men and Women

Daeppen

Smith²,

Danko³

et al. 2000

Alcohol and Alcoholism

134

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-This paper examines the clinical characteristics associated with tobacco use and nicotine dependence in a large sample of alcohol-dependent subjects. The goal was to determine if the characteristics of the alcohol use history were associated with the smoking status, even after controlling for additional characteristics, such as the antisocial personality disorder, other drug dependence and gender. As part of the Collaborative Study on the Genetics of Alcoholism, a semi-structured interview, including a detailed history of alcohol and tobacco use, was administered to 1005 alcohol-dependent men and women, made up of 658 (65.5%) current smokers, 167 (16.6%) former smokers, and 180 (17.9%) non-smokers. Among former smokers, 50.3%, and among current smokers, 72.8% had ever been nicotine-dependent (DSM-III-R). Current smokers and nicotine-dependent subjects had a greater severity of alcohol dependence, even as evaluated through logistic regression analyses in which gender and associated diagnoses were considered. The data also enabled us to study the relationships among depression, nicotine dependence, and alcohol dependence, with most of the correlation occurring for substance-induced, not independent, mood disorders.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Clinical Correlates of Cigarette Smoking and Nicotine Dependence in Alcohol-Dependent Men and Women

Daeppen

Smith²,

Danko³

et al. 2000

Alcohol and Alcoholism

134

View full text Add to dashboard Cite

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“…22 This is important for several reasons. Firstly, it shows that these women experience a significant burden of disease.…”

Section: Discussionmentioning

confidence: 99%

Risk factors for substance use in pregnant women in South Africa

et al. 2012

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“…This is a family pedigree study that begins with an alcohol-dependent proband in treatment and gathers data from that subject and all available appropriate relatives (4,(7)(8)(9)(10). Subjects in the Collaborative Study on the Genetics of Alcoholism sample were included regardless of additional diagnoses, with the only exclusions occurring for individuals who were unable to speak English, those with evidence of severe debilitating diseases such as AIDS, those with recent heavy intravenous drug use, and subjects who had fewer than two relatives available for interview.…”

Section: Methodsmentioning

confidence: 99%

Clinical Implications for Four Drugs of the DSM-IV Distinction Between Substance Dependence With and Without a Physiological Component

Schuckit

Daeppen²,

Danko³

et al. 1999

AJP

109

105

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Objective: The DSM-IV work group asked researchers and clinicians to subtype substance dependent individuals according to the presence or absence of physiological symptoms. A recent report from the Collaborative Study on the Genetics of Alcoholism demonstrated that among alcohol-dependent men and women, a history of tolerance or withdrawal was associated with a more severe clinical course, especially for individuals with histories of alcohol withdrawal. This article evaluates similar distinctions among subjects in the collaborative study who were dependent on marijuana, cocaine, amphetamines, or opiates. Method: Structured interviews gathered information from 1,457 individuals with a lifetime diagnosis of marijuana dependence, 1,262 with histories of cocaine dependence, 647 with amphetamine dependence, and 368 subjects with opiate dependence. For each drug, the clinical course was compared for subjects whose dependence included a history of withdrawal (group 1), those dependent on each drug who denied withdrawal but reported tolerance (group 2), and those who denied both tolerance and withdrawal (group 3). Results: The proportion of dependent individuals who denied tolerance or withdrawal (group 3) ranged from 30% for marijuana to 4% for opiates. For each substance, individuals in groups 1 and 2 evidenced more severe substance-related problems and at least a trend for greater intensities of exposure to the drug; those reporting withdrawal (group 1) showed the greatest intensity of problems. Conclusions: The designation of dependence in the context of tolerance or withdrawal identifies individuals with more severe clinical histories. These results support the importance of the designation of a physiological component to dependence, especially for people who have experienced a withdrawal syndrome.(Am J Psychiatry 1999; 156:41-49)

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The clinical course of alcohol-related problems in alcohol dependent and nonalcohol dependent drinking women and men.

Cited by 131 publications

References 33 publications

Clinical Correlates of Cigarette Smoking and Nicotine Dependence in Alcohol-Dependent Men and Women

Clinical Correlates of Cigarette Smoking and Nicotine Dependence in Alcohol-Dependent Men and Women

Risk factors for substance use in pregnant women in South Africa

Clinical Implications for Four Drugs of the DSM-IV Distinction Between Substance Dependence With and Without a Physiological Component

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