The Clinical Course of 234 Neoplasms of the Bladder in North-East Scotland

Abstract

A NUMBER of American writers have reported the clinical course of patients with bladder tumours in the past fifteen years, but there have been few reports from Britain. Recent series are described by Payne (1959) from London, Thompson (1960) from Newcastle, and Francis (1961) from Alberta. This paper is a survey of patients who had turnours of the bladder treated in Aberdeen between 1946 and 1957. The starting point was a collection of 357 biopsy reports of tumours of the urinary tract in the records of the Pathology Department of Aberdeen Medical School. From these reports, 234 patients were found whose case records were complete and who suffered from neoplasms of the bladder. The case records of a further sixty-three patients were incomplete or unobtainable, making a total of 297. Therefore, the average yearly incidence for the twelve years covered by the survey is twenty-five cases in the population of roughly 400,000 served by the Aberdeen Teaching Hospitals. The rate per million per year is therefore sixty-two, which accords well with the figure of seventy-three reported by Case (1953) for the national yearly average incidence. However, between 1946 and 1957 there was a steady rise in the number of cases diagnosed per year. The 234 fully documented patients were scattered uniformly over North-East Scotland and there was no particular concentration in any particular district or town.

Natural Killer Cell Activity and Response to Phytohaemagglutinin Compared with the Histological Diagnosis of Patients with Transitional Cell Carcinoma of the Bladder

“…About 15% of patients with newly diagnosed (Tl) bladder tumours subsequently develop invasive tumours (Mills, 1964). Information regarding the prognosis of these patients and of those patients whose tumour is invasive when newly diagnosed (T2-4) is mainly limited to clinical and histological examination.…”