The Clinical Characteristics and Treatment responses of Tuberculosis in Patients with Malignancy on Anti-cancer Chemotherapy

Kim, Deog K.; Lee, Sei Won; Ko, Dong Seok; Yoo, Chul Gyoo; Kim, Young Whan; Han, Sung Koo; Shim, Young‐Soo; Yim, Jae-Joon

doi:10.1378/chest.126.3.888

Cited by 5 publications

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“…Reactivation of latent tuberculosis (TB) may be induced by the administration of cytotoxic chemotherapy and high dose corticosteroid therapy [ 1 , 3 , 4 , 8 ]. A high index of suspicion should be maintained in immunocompromised individuals presenting with clinical and radiological manifestations compatible with TIs [ 6 , 7 , 9 - 16 ]. At times, an empirical anti-tuberculous therapy should be employed to prevent further clinical deterioration and a possible lethal outcome that may be associated with delayed diagnosis and late institution of treatment [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

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Infections caused by mycobacterium tuberculosis in patients with hematological disorders and in recipients of hematopoietic stem cell transplant, a twelve year retrospective study

Al-Anazi

Al-Jasser

Evans

2007

Annals of Clinical Microbiology and Antimicrobials

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Section: Introductionmentioning

confidence: 99%

“…The efficacy of anti-TB chemotherapy in patients with hematological malignancies and in recipients of HSCT is well documented [ 4 , 9 ]. However, drug resistance, non-compliance with medications and the presence of advanced and miliary forms of tuberculosis remain real challenges [ 4 , 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

Infections caused by mycobacterium tuberculosis in patients with hematological disorders and in recipients of hematopoietic stem cell transplant, a twelve year retrospective study

Al-Anazi

Al-Jasser

Evans

2007

Annals of Clinical Microbiology and Antimicrobials

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A Dutch patient with diffuse panbronchiolitis successfully treated with clarithromycine

Vries

Suylen

Wouters

2007

Respiratory Medicine Extra

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Genetic predisposition to diffuse panbronchiolitis

Keicho

Hijikata

2011

Respirology

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Diffuse panbronchiolitis is characterized by chronic inflammation in respiratory bronchioles and sinobronchial infection. The pathophysiology accompanying the persistent bacterial infection is noteworthy for the accumulation of lymphocytes and foamy macrophages around the small airways, for mucus hypersecretion, and for the number of neutrophils in the large airways. Until the establishment of long-term macrolide therapy, the prognosis was generally poor. Case studies of diffuse panbronchiolitis in East Asians, including Japanese, Koreans and Chinese, have frequently been reported, and genetic predisposition to the disease has been assumed in Asians. Immunogenetic studies revealed a strong association with human leukocyte antigen (HLA)-B54 in Japanese, whereas an association with HLA-A11 was reported in Koreans. These findings imply that a major susceptibility gene may be located between the HLA-A and HLA-B loci on the short arm of human chromosome 6. We have recently cloned novel mucin-like genes in this candidate region. In addition to accumulated knowledge of classical HLA genes and mucin genes, further analysis of newly identified genes may provide insights into the pathogenesis of the disease.

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The Clinical Characteristics and Treatment responses of Tuberculosis in Patients with Malignancy on Anti-cancer Chemotherapy

Cited by 5 publications

References 0 publications

Infections caused by mycobacterium tuberculosis in patients with hematological disorders and in recipients of hematopoietic stem cell transplant, a twelve year retrospective study

Infections caused by mycobacterium tuberculosis in patients with hematological disorders and in recipients of hematopoietic stem cell transplant, a twelve year retrospective study

A Dutch patient with diffuse panbronchiolitis successfully treated with clarithromycine

Genetic predisposition to diffuse panbronchiolitis

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