The clinical and histopathologic spectrums of urticarial vasculitis: Study of forty cases

Cellular and Molecular Dynamics in Exercise-Induced Urticarial Vasculitis Lesions

“…1 Based on the histologic findings of fully developed lesions, the presence of vessel damage, including swelling of endothelial cells, fibrinoid necrosis, a predominantly neutrophilic perivascular infiltrate with nuclear debris, and extravasated red blood cells, has been regarded as the histologic criterion for differentiating this disorder from urticaria. 1,2 However, because skin biopsy specimens of urticarial vasculitis are routinely prepared from the fully developed lesions and the early lesions have not been examined histologically, the key biological events leading to the development of leukocytoclastic vasculitis remain unknown. This is probably due to the paucity of patients in whom characteristic lesions of urticarial vasculitis can be reproduced by physical challenge, 3 despite sporadic case reports of urticarial vasculitis induced by administration of drugs 4 and by exposure to a cold stimulus.…”

Urticaria-Associated Recurrent Glomerulonephritis with a Favorable Response to Indomethacin

“…Renal disease is present in 10-30% of the patients with urticarial vasculitis, and is usually mild [2,3] but, as in this patient, it may be severe [6,8). Renal biopsy usually shows diffuse proliferative or membranoproliferative glomerulonephritis [1,3,[6][7][8][9][10], Hypocomplementemia is not always present.…”

Membranoproliferative Glomerulonephritis Associated with Hypocomplementemic Urticarial Vasculitis after Complete Remission of Membranous Nephropathy

“…The renal prognosis seems to be better in HUVS than in SLE. In many cases of HUVS, steroid therapy was effective [1, 16], and few cases in adults progressed to end-stage renal disease [17]. Wisnieski et al [1]reported that the predominance of MPGN lesions in HUVS is another difference between them.…”