The chronicles of inflammation: uncovering of distinct patterns of NET degradation products
Janina Schoen,
Marco Muñoz-Becerra,
Jasmin Knopf
et al.
Abstract:AimsNeutrophils and neutrophil extracellular traps (NETs) play multifaceted roles in inflammatory diseases. If the balance of NET formation and clearance is disturbed, they contribute to the development and pathogenesis of a plethora of inflammatory diseases. They promote inflammation and tissue degradation, and occlude vessels and ducts. This study focused on the presence of NET remnants generated during the clearance by nucleases and phagocytes.MethodsNET associated parameters in serum and plasma samples fro… Show more
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