The chronically symptomatic vulva: aetiology and management

Abstract

Objective To determine the causes and management of chronic vulval symptoms and to compare the findings in patients first presenting to a gynaecologist with those in patients first presenting to a dermatologist. Design A prospective study of 144 patients, approximately half each being referred to a gynaecologist and a dermatologist. Diagnosis was based on clinical history, vulvoscopy, vulval biopsy and bacteriology. Biopsies were examined by a histopathologist experienced in dermatopathology and gynaecological pathology. Results The two patient groups were similar in both range and frequency of conditions. The commonest cause of chronic vulval symptoms was dermatitis, which was found in 64% of our patients. Dermatitis occurred alone in 55% and was found in association with histological evidence of human papilloma virus (HPV) in a further 9%. These patients responded to simple dermatological methods, mainly topical corticosteroids. Histopathological evidence of HPV was encountered in only 23% of our patients, and of these 36% also demonstrated dermatitis on biopsy. Most responded to topical corticosteroids. Another 7% had lichen sclerosus, and all responded to potent topical corticosteroid. The remaining 15% demonstrated a range of diagnoses, including psoriasis, dysaesthetic vulvodynia, vulval intraepithelial neoplasia (VIN) and chronic candidiasis. The majority of patients had a corticosteroid responsive dermatosis rather than a gynaecological condition. Conclusions The majority of patients with a chronically symptomatic vulva who present to either a gynaecologist or a dermatologist have a dermatological condition that responds to simple dermatological treatments. We believe that the presence or absence of the human papilloma virus is not relevant to most patients with a chronically symptomatic vulva and treatments should not be aimed at eradicating this virus. Histopathologists and gynaecologists who have focused on gynaecological disorders have often missed simple dermatological conditions that are easily treatable.

Liquen Simple Crónico Vulvar Unilateral

“…Los pilares del tratamiento son el uso de antihistamínicos por vía oral y corticoides ultrapotentes tópicos (3,4). El uso de antihistamínicos tiene por objetivo disminuir el prurito, especialmente nocturno, donde el rascado es inconsciente.…”

Vulvar Dermatoses

“…Vulvar dermatiti olan hastaların yaklaşık %75'inde atopik dermatit öyküsü olduğu saptanmıştır. Bu gruptaki hastalarda en sık görülen lezyonlar labialar arasında, perianal bölgede ve natal kleftte eritemdir (8,18).…”

Lichen sclerosus and other conditions mimicking vulvovaginal candidiasis

“…Among the possible etiologies, non-neoplastic epithelial disorders represent an underappreciated yet common cause of symptoms. For example, in a prospective study of 144 patients evaluated in Australia for chronic vulvar symptoms [4], 64% had dermatitis, 7% had lichen sclerosus, and 15% had a range of other conditions. Only 6% had chronic candidiasis.…”