Abstract:This leaves uncertainty on whether a mutation has been corrected or compounded. However, it has been hypothesized that tagging of mismatch regions, so that both strands are epigenetically marked as uncertain, would make it possible over numerous generations for mutations to be corrected (biased conversions) whenever asymmetry is detected. Thus, variation would decrease and members of a species would remain within its bounds.Intriguingly, new experimental studies show that, when chromosomally interpreted, PRDM9… Show more
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