The chorionic bump associated with acrania – case report

Węgrzyn, Piotr; Brawura-Biskupski-Samaha, Robert; Borowski, Dariusz; Górski, A; Wielgoś, Mirosław

doi:10.17772/gp/1680

Cited by 10 publications

(15 citation statements)

References 12 publications

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“…Although it has been postulated that a chorionic bump may represent an anembryonic gestation or demise of an embryo in a twin pregnancy, 5 the prevailing hypothesis is that a chorionic bump represents a hematoma or hemorrhage, as evidenced by hyperechogenicity on sonography, reported T1 hyperintensity on magnetic resonance imaging, 1 and the single case with radiologic‐pathologic correlation showing hemorrhage between villus formation and a decidual reaction under the microscope 3 . Whatever the exact etiology, the fact that 91% of live births (31 of 34) in this study showed resolution of the chorionic bump by 12 weeks suggests the possibility that the body can reabsorb the underlying process.…”

Section: Discussionmentioning

confidence: 99%

“…Since the sonographic finding of a chorionic bump was first described 9 years ago, only 4 additional articles about it have been published in the literature. These include a retrospective review from Europe 2 and 3 isolated case reports, 3 – 5 1 of which was a tubal ectopic pregnancy with histopathologic analysis supporting the prevailing hypothesis that a chorionic bump represents a hematoma. However, given the inability to obtain pathologic confirmation in most cases and the relative dearth of published information, chorionic bumps remain largely of uncertain etiology and importance at this time.…”

mentioning

confidence: 96%

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Chorionic Bump on First‐Trimester Sonography

Arleo

Troiano

2015

J of Ultrasound Medicine

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Objectives The purpose of this study was to determine the live birth rate of pregnancies with a diagnosis of a chorionic bump, a convex bulge from the choriodecidual surface into the first‐trimester gestational sac. Methods Pregnant patients at least 18 years old with the finding of a chorionic bump on first‐trimester sonography were included in this prospective observational study. The independent variables were chorionic bump size and number and presence or absence of a history of infertility or coagulation disorder. The primary end point was pregnancy outcome. Results During the 4‐year study period, 52 pregnancies had a diagnosis of a chorionic bump. Overall, 34 resulted in live births, corresponding to an absolute live birth rate of 65%, and 18 were nonviable. Forty‐one chorionic bump pregnancies were otherwise normal (ie, pregnancies in which a gestational sac, yolk sac, and embryo with heartbeat were seen at some point), and in this subset, the live birth rate was 83% (34 of 41). All pregnancies with more than 1 chorionic bump (4) ended in demise (100%). The average maximum dimension of the chorionic bump was 1.3 cm (range, 0.5–3.8 cm); however there was not a statistically significant correlation between chorionic bump size and pregnancy outcome (P = .5866; odds ratio, 0.54; 95% confidence interval, 0.06–5.01). Nine patients (17%) had a history of infertility treatment, and 4 (8%) had a history of coagulation disorder. Only 1 chorionic bump pregnancy was associated with a birth defect. Conclusions The live birth rate in our chorionic bump cohort was 65% overall and even higher (83%) if the pregnancy was otherwise normal. The clinical implication is that a chorionic bump on first‐trimester sonography is not necessarily associated with a guarded prognosis.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 96%

Chorionic Bump on First‐Trimester Sonography

Arleo

Troiano

2015

J of Ultrasound Medicine

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“…After the late first‐trimester period, the possibility of fetal demise or pregnancy loss later on in pregnancy decreases dramatically, especially in fetuses with no abnormal findings on scan . The incidental reported association with ectopic pregnancy, fetal malformations such as acrania or forearm reduction defect, and chromosomal abnormalities were also absent from our series, although one of our fetuses had trisomy 21.…”

Section: Discussionmentioning

confidence: 61%

“…This is true for the general population as well as for patients with a history of infertility treatment. A computerized search of the Pubmed/MEDLINE database using the term “chorionic bump” revealed six larger series describing between eight to 57 cases and eight isolated reports describing one or two cases. Our report adds an additional 23 cases, for a total of 190 cases reported in the English literature.…”

Section: Discussionmentioning

confidence: 99%

“…This led to the conclusion that this sonographic feature is associated with a guarded prognosis. 1 Until now, the vast majority of cases of chorionic bump have been detected in pregnancies presenting before 11 weeks' gestation, [1][2][3][4][5][6][7][8][9][10][11][12][13][14] with only one report including cases referred for nuchal translucency thickness measurements at 11 to 13 weeks' gestation. 9 However, the latter report was based on pregnancies with available cytogenetic studies, and neither specific clinical details nor pregnancy outcomes were reported.…”

Section: Introductionmentioning

confidence: 99%

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Chorionic bump at 11 to 13 weeks' gestation: Prevalence and clinical significance

Sepúlveda¹

2019

Prenatal Diagnosis

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Objective To gather additional data on pregnancy outcome when a chorionic bump is detected at the time of the 11‐ to 13‐week scan. Methods The presence of a chorionic bump was prospectively recorded in a database of women presenting for their first‐trimester sonographic screening. Clinically relevant information was obtained by reviewing ultrasound reports and medical records or contacting the referring obstetrician or the parents themselves. Results During a 4.5‐year study period from June 2014 to December 2018, a chorionic bump was identified in 23 out of 3375 pregnancies, for a prevalence of 1/147 or 0.7%. All women were asymptomatic at the time of evaluation. The chorionic bump was single in 21 (91%) cases, located in the central part of the placenta in 17 (74%) cases, and the median largest diameter was 20 mm (range, 10‐43). Although the placenta was low‐lying in 14 (61%) cases, all but one patient had a normally located placenta at the midtrimester anatomy scan. With the exception of one pregnancy complicated with trisomy 21, the outcome was universally good. Conclusion Our experience suggests that a chorionic bump detected during the 11‐ to 13‐week scan is usually a transient, is incidental finding, and probably has no clinical significance.

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New insight on etiology: A chorionic bump with partial mole pregnancy case report from Syria

Hamed,

Alhouri,

Allahham

et al. 2024

J of Clinical Ultrasound

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This case report presents the association of a chorionic bump with a partial mole pregnancy in a 37‐year‐old G3P2 woman. The differential diagnosis of a partial mole was considered after transvaginal ultrasonography revealed a chorionic bump. Subsequent pathological analysis confirmed the diagnosis. While the etiology of the chorionic bump remains dubious, we hypothesize an alternative explanation for chorionic bump formation based on the presence of three unique pathological features: necrosis, edema, and hemorrhage.

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The chorionic bump associated with acrania – case report

Cited by 10 publications

References 12 publications

Chorionic Bump on First‐Trimester Sonography

Chorionic Bump on First‐Trimester Sonography

Chorionic bump at 11 to 13 weeks' gestation: Prevalence and clinical significance

New insight on etiology: A chorionic bump with partial mole pregnancy case report from Syria

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