The cholinergic system and the dental pulp

Avery, James K.; Chiegojr, D

doi:10.1007/978-94-009-0421-7_19

Cited by 7 publications

(2 citation statements)

References 98 publications

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“…Other small nerve fibers of the same diameter as C-fibers (0.2-1.0 |xm) in the pulp are postganglionic sympathetic nerves. Although parasympathetic nerves in the pulp have been proposed (Avery and Chiego, 1990), and acetylcholine and the neuropeptide VIP (vasoactive intestinal peptide) have been shown to co-exist in cholinergic parasympathetic nerves, their role in the regulation of pulpal blood flow is not clear. The vasodilation of pulpal blood vessels following acetylcholine infusion is probably due to release of nitric oxide by endothelial cells (Lohinai etai, 1995).…”

Section: (B) Innervation Of Dentin (1) Developmentalmentioning

confidence: 99%

Dynamics of the Pulpo-Dentin Complex

Pashley

1996

Critical Reviews in Oral Biology & Medicine

369

246

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Dentin has a relatively high water content due to its tubular structure. Once dentin is exposed, this intratubular water is free to move in response to thermal, osmotic, evaporative, or tactile stimuli. Fluid shifts across dentin are thought to cause sufficient shear forces on odontoblasts, nerve endings, nearby fibroblasts, and blood vessels to cause significant mechanical irritation, disruption, or damage, depending on the magnitude of the fluid shift. Even in the absence of fluid shifts, the water-filled tubules provide diffusion channels for noxious (i.e., bacterial products) substances which diffuse inward toward the pulp, where they can activate the immune system, provide chemotactic stimuli, cytokine production, and produce pain and pulpal inflammation. Viewed from this perspective, dentin is a poor barrier to external irritants. However, pulpal tissues react to these challenges by increasing the activity of nerves, blood vessels, the immune system, and interstitial fluid turnover, to make the exposed dentin less permeable either physiologically, via increased outward fluid flow, or microscopically, by lining tubules with proteins, mineral deposits, or tertiary dentin, thereby enhancing the barrier properties of dentin, and providing additional protection to pulpal tissues. These reactions involve dentin and pulp, both in the initiation of the processes and in their resolution. These responses of the dental pulp to irritation of dentin demonstrate the dynamic nature of the pulpo-dentin complex.

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Section: (B) Innervation Of Dentin (1) Developmentalmentioning

confidence: 99%

Dynamics of the Pulpo-Dentin Complex

Pashley

1996

Critical Reviews in Oral Biology & Medicine

369

246

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“…At the center of each tooth is pulp, a nonmineralized tooth tissue composed of cells, matrix, vascularization, and nerves. There are five primary functions of pulp, including inductive, formative, protective, nutritive, and reparative 1,2 . When the pulp becomes inflamed due to bacterial, physical, or chemical factors, it can lose its function.…”

Section: Introductionmentioning

confidence: 99%

Efectivenesse of three pulp capping materials on cellular response of pulp tissue

Kusuma

2023

Odonto: Dental Journal

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Background: Pulp capping is a treatment that utilizes medications to preserve pulp vitality. Ca(OH)2, mineral trioxide aggregate (MTA), and biodentine are presently the most common pulp capping medications. As pulp capping materials, Ca(OH)2 and MTA are known to have several weaknesses. Biodentine has been created in an effort to mitigate the drawbacks of Ca(OH)2 and MTA. Thus, the purpose of this study is to compare the efficacy of three pulp capping medications in reducing inflammation and accelerating pulp regeneration. Methods: Total 48 male Wistar rats, that were divided into 4 groups, namely 1st control group, 2nd MTA group, 3rd biodentine group, and 4th Ca(OH)2 group. Maxillary 1st molar teeth of rats were prepared using round bur no. 080 perpendicular to the tooth axis to a depth of 1mm, until a reddish color appeared on the pulp. Furthermore, pulp capping medicament was applied to the deepest points, and temporary fillings were made with Zn2(PO4)3. Decapitation was carried out on days 4 and 7 to count the number of neutrophil cells, macrophages, odontoblast-like cells, and fibroblasts. Data were analyzed using One-way ANOVA (p

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Dynamics for Pulp-Dentin Tissue Engineering in Operative Dentistry

Tziafas¹

2010

Synthesis Lectures on Tissue Engineering

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The cholinergic system and the dental pulp

Cited by 7 publications

References 98 publications

Dynamics of the Pulpo-Dentin Complex

Dynamics of the Pulpo-Dentin Complex

Efectivenesse of three pulp capping materials on cellular response of pulp tissue

Dynamics for Pulp-Dentin Tissue Engineering in Operative Dentistry

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