The Cholera outbreak in Karachi, Pakistan: Challenges, efforts and recommendations

Khan, Hira Anas; Masood, Waniyah; Siddiqui, Amna; Ahmad, Shkaib; Salman, Yumna; Yasir, Mohammad

doi:10.1016/j.amsu.2022.103873

Cited by 11 publications

(17 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In age of 7-12 years a child usually tries to get independent in his daily cleaning habits and chance of being exposed to infections are high. Hand washing is a major tool to combat the infectious and water borne diseases 19 (Pal M, et al, 2018).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Cholera: An Outbreak Causing Diarrhoea; A Serious Threat to Population

Ishfaq¹,

Naqvi²,

Javeed³

et al. 2022

PJMHS

View full text Add to dashboard Cite

Objective: To evaluate the association of Vibrio cholera infection with age and gender. To develop the antibiotic sensitivity pattern for Vibrio cholera against commercially available preparations in market. Study Design: Descriptive cross-sectional Place and duration: Study was conducted at department of Pathology, Nishtar Medical University and Hospital Multan, in the months from April to September, 2022. Methodology: Total 191 Stool samples were sent to Microbiology laboratory, Pathology department of hospital which was included in this study. These samples were from Nishtar Hospital various wards and from CEO office. After successful isolation of bacteria the antibiotic sensitivity were tested by Kirby-Baur Disc Diffusion Method. Results: During the outbreak of Vibrio cholera in our area, 10.99% cases were detected in whole diseased population. Mean age of patients who developed Vibrio cholera was 7.68 + 0.66 years. Gender showed no discrimination as both males and females were almost equally affected. Age and gender were not found statistically significant (p=0.740 and p=0.329). The sensitivity was measured for three antibiotic drugs (Ampicillin, Erythromycin and Tetracycline). Among them only Ampicillin showed 50% sensitivity whiles other two antibiotics were 100% sensitive. Conclusion: Unhygienic environment especially in pediatrics group has showed to be the main risk factor in the outbreaks of cholera. Proper disposal of waste, especially from infected persons, to keep it segregated from drinking water along with awareness programs are the need of hour to prevent further outbreaks. Keywords: Kirby-Baur Disc Diffusion Method, Vibrio cholera, Outbreak, Pediatrics, Ampicillin, Erythromycin and Tetracycline

show abstract

Section: Discussionmentioning

confidence: 99%

“…In July 2002 and June 2003 an outbreak was reported in a village outside the Karachi. According to the report 69 cases were positive in that village at the time of surveillance 13 (Khan HA, Masood W et al, 2022). In recent times, Karachi has again faced a surge of cholera outbreak in 2022.…”

Section: Introductionmentioning

confidence: 99%

Cholera: An Outbreak Causing Diarrhoea; A Serious Threat to Population

Ishfaq¹,

Naqvi²,

Javeed³

et al. 2022

PJMHS

View full text Add to dashboard Cite

show abstract

“…Another notable problem that should not be overlooked is the lack of proper surveillance and testing for the disease [ 7 ]. Mostly cholera is diagnosed upon clinical suspicion, but this diagnosis is confirmed only by microbiological stool cultures or by molecular studies such as PCR.…”

Section: Challenges and Effortsmentioning

confidence: 99%

“…The most recent outbreak began in Sindh in 2022. The disease has made its way into Baluchistan and Punjab in the last few months [ 7 ]. A total of 290 confirmed cases of cholera had been reported in these provinces as of 27 May [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

The cholera outbreak in Lahore, Pakistan: challenges, efforts and recommendations

et al. 2022

Self Cite

View full text Add to dashboard Cite

The Punjab health authorities have declared a cholera outbreak with over 2000 acute diarrheal cases being reported in Lahore in April 2022 and 25 laboratory-confirmed cases as of 27 May 2022. Overpopulation, poor sanitation, and a substandard water drainage system contribute to the spread of cholera. The increasing hydro-toxicity of underground water is another challenge to the disease spread. The lack of public awareness about the disease and their poor hygiene practices serve as a portal for the disease to spread to humans. There is a need to establish an effective surveillance system, increase public awareness, and implement the WHO-recommended plan for cholera control. This includes the provision of drugs and diagnostic kits to healthcare centres, the supply of clean water, and the development of a drainage system for sewage and rainwater.

show abstract

“…1 ) [ 2 ]. However, the accurate numbers are expected to be higher than the announced ones due to the lack of proper reporting and surveillance [ 3 ]. Furthermore, the outbreaks occurred in different countries in Asia, Africa, and Europe.…”

mentioning

confidence: 99%