The crystallographic orientation of C 2/m amphiboles has been depicted incorrectly since the standardization of amphiboles in C 2/m. Texts citing the early optical work on amphiboles reference structures drawn in the I 2/m cell, for which the optical orientation is correct. When C 2/m became the standard space group, the optical orientation, (hkl), and crystallographic axes depicted in crystal form drawings were never revised. Using the methods outlined by Gunter and Twamley (2001) combined X-ray and optical methods on single crystals of amphiboles reveal the discrepancy between axes. In the correct orientation of a typical C 2/m amphibole, the physical optical orientation should have never changed from its position outlined in the Tschermak setting as shown in Ford and Dana (1932), however, the crystallographic axes and (hkl) should have changed to accommodate the difference between the I 2/m cell and the C 2/m cell. This error may perpetuate a misunderstanding between the crystallographic setting and optical orientation of clinoamphiboles, which is an important relationship for orientation-dependent analytical methods. Enclosed in this study is the correction of crystallographic axes for crystal form drawings for C 2/m amphiboles, along with an outline of methodology and updates to the spreadsheet EXCELIBR. The methods applied in this study utilize relationships between crystallographic and optical vectors and include an addendum to those presented by Gunter and Twamley (2001), which is applicable to arbitrary reference positions on spindle stages.