The Chemotherapy and Serum Therapy of Pneumococcus and Streptococcus Meningitis: Vi. The Cerebral-Cisternal-Spinal Lavage Method of Treatment for Septic Meningitis

Fortunately while pneumococcus and streptococcus meningitis are uncommon complications of paranasal sinusitis, otitis media and mastoiditis, yet the dreadful mortality of these meningeal infections, despite newer methods of treatment,1 warrants serious consideration of the possible value of immunologic measures for their prevention.In a previous communication 2 we have shown that pneumococcus meningitis of rabbits, especially that produced by type I pneumococcus, may be prevented by the administration of Felton's antipneumococcus serum.The results with types II and III pneumococci were less pronounced but not without some encouragement, as was likewise the prevention of streptococcus meningitis, produced with a hemolytic strain, by the administration of antistreptococcus serum with special reference to scarlet fever antitoxin.On the basis of these results we advised the more frequent bacteriologic examination of the secretions in cases of paranasal sinusitis and mastoiditis before or during operation and the prompt administration of polyvalent antipneumococcus or antistreptococcus serum to those in whom the surgeon feared the possible development of meningitis.

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Gram-negative meningitis following head wounds. With especial reference to infection with coliform bacilli

Lewin

1948

Journal of British Surgery

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OF the various bacteria commonly found in war importance; although these cases were not studied wounds, the Gram-positive organisms, clostridia, fully bacteriologically, it is clear from the records staphylococci, and streptococci claim the first that these were the organisms responsible for nearly attention by reason of their pathogenicity. I n the all the infections, and that of the 71 fatalities in the first world war the results of treatment of 250 head series " . . . no less than 43 were due to, or at least wounds given bv Cushing (1918) emDhasized their associated with, an intracranial infection-meningitis --. . , -___ in 14, ventriculitis in 12, encephalitis-usuailygas infection-in 9, and abscess in 8 , . .

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The Chemotherapy and Serum Therapy of Pneumococcus and Streptococcus Meningitis: Vi. The Cerebral-Cisternal-Spinal Lavage Method of Treatment for Septic Meningitis

Cited by 4 publications

References 2 publications

The Chemotherapy and Serum Therapy of Pneumococcus and Streptococcus Meningitis: Vii. The Intracarotid Treatment for Experimental Pneumococcus Meningitis

The Chemotherapy and Serum Therapy of Pneumococcus and Streptococcus Meningitis: Vii. The Intracarotid Treatment for Experimental Pneumococcus Meningitis

The Specific Prophylaxis of Pneumococcus and of Streptococcus Meningitis: Ii. Vaccine Prophylaxis

Gram-negative meningitis following head wounds. With especial reference to infection with coliform bacilli

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