The Chemistry of Aldehydes and Ketones in the Synthesis of Heterocycles - Historical
Reactions with a New and Green Perspective
Flavia Martins da Silva,
Joel Jones Junior,
July A. Hernández Muñoz
Abstract:The reactivity of aldehydes and ketones carries great potential for multicomponent heterocyclizations.
These reactions are convergent and highly versatile in the development of synthetic methodologies for
compound families, displaying variations in substituents in their structures. Therefore, they have been regarded
as an important tool in the field of Green Chemistry. Furthermore, they prove to be very useful in studies of
biological activity, where small structural modifications can result in significant dif… Show more
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