The Chemical Industry

Use of statistical design of experiments in the optimization of Ar–O2 low-pressure plasma treatment conditions of polydimethylsiloxane (PDMS) for increasing polarity and adhesion, and inhibiting hydrophobic recovery

“…PDMS is biocompatible amorphous polymer [1,2] commonly used in medical devices including contact lenses, denture liners, wound dressing, drug delivery systems, catheters, ear correctors and implants. The particular properties of PDMS derived from its chemical structure made of siloxane (Si-O) backbone with methyl pendant groups and its higher ionic character derived from the higher electronegativity of oxygen and the lower electronegativity of silicon with respect to that of carbon.…”

Gas-phase pyrolysis of 2-heteroaromatic-1-dimethylaminoethylenes: Kinetic and mechanistic study

“…1 [1,2-b]pyran-3-carbonitrile (2). A mixture of ethyl cyanocetate and ammonium acetate was treated with 2-acetyl-1-naphthol.…”

“…Functionally substituted heteroaromatics are interesting as potential pharmaceuticals [1], agrochemicals [2], and as dye intermediates [3], and their chemistry is now receiving considerable attention [4,5]. In conjunction with our recent interest in adopting the environmentally friendly gas-phase technique in synthetic organic chemistry, we have previously reported on the utility of this technique for synthesis of substituted nitriles [6,7], ketones [8], and functionally substituted heteroaromatics.…”

Studies with enamines: Functionally substituted enamines as aldehyde equivalents in Gewald reaction

“…[1][2][3][4] Since aminothiophenes are important intermediates in dye preparations, 5,6 in the pharmaceutical industry and as a precursors for other thiophenes employed in several high technology applications, 7 this methodology has been extensively utilized for the preparation of a variety of aminothiophenes via reacting ketones and aldehydes with active methylene carbonitriles and sulfur in presence of a base. [8][9][10][11] In the context of our interest in aminothiophenes as precursors to arylazo dyes 12,13 we became interested in 2-amino-4-unsubstituted thiophenes with a functional substituent at C-5.…”