The Chemical Constituents of Capparis Spinosa of Jordanian Origin

Khanfar, Monther A.; Sabri, Salim S.; Zarga, Musa H. Abu; Zeller, Klaus‐Peter

doi:10.1080/10575630290034302

Cited by 36 publications

(16 citation statements)

References 4 publications

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“…Its ESI-MS contained an additional peak m/z 267, corresponding to the fatty acyl residue. The 1 H-and 13 C-NMR spectra of 4 were similar to those of octadecanoate and β-sitosteryl glucoside (Khanfar et al, 2003). The 1 H-NMR spectrum of 4 showed a huge peak at 1.2-1.3 ppm corresponding to the fatty acid chain protons.…”

Section: Resultsmentioning

confidence: 66%

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A potential inhibitor of rat aortic vascular smooth muscle cell proliferation from the pollen of Typha angustata

et al. 2010

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By various chromatographic methods, three flavonoids, (2S)-naringenin (1), isorhamnetin 3-O-(2-O-α-L-rhamnopyranosyl) β-D-glucopyranoside (2), typhaneoside (3), and two sterol glycosides, β-sitosterol-3-O-(6-octadecanoyl) β-D-glucopyranoside (4) and β-sitosterol-3-O-(6-octadeca-9Z,12Z-dienoyl) β-D-glucopyranoside (5), were isolated from the pollen of Typha angustata. Their structures were determined on the basis of spectroscopic analyses. The flavonoids (1-3) were evaluated for their effects on the viability and proliferation of rat aortic smooth muscle cells. (2S)-naringenin (1) significantly inhibited cell proliferation in a dose-dependent manner without cytotoxic at concentrations of 30, and 50 μM; it reduced the number of cells following PDGF-BB treatment to 1.83 ± 0.30 × 10(4) and 2.20 ± 0.60 × 10(4) cells/well, respectively. These findings suggest that (2S)-naringenin has antiproliferative effects on aortic smooth muscle cells.

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Section: Resultsmentioning

confidence: 66%

“…Alkaline hydrolysis of compound 4 yielded β-sitosterol, glucose, and octadecanoic acid (identified by GC-MS). Collectively, the spectral data indicated that the structure of compound 4 was β-sitosterol-3-O-(6-octadecanoyl) β-D-glucopyranoside (Khanfar et al, 2003).…”

Section: Resultsmentioning

confidence: 97%

A potential inhibitor of rat aortic vascular smooth muscle cell proliferation from the pollen of Typha angustata

et al. 2010

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“…The presence of alkaloid, such as stachydrine, cadabicine, capparispine, capparispine 26-O-β-d-glucoside, cadabicine 26-O-β-d-glucoside hydrochloride was demonstrated in fruit and roots, but the alkaloid content of C . spinosa root was higher than that of its fruits [14][15][16][17] and quercetin content was higher in fruits than in roots [18]. Indoleglucosinolates such as glucobrassicin, neoglucolorassicin and methoxyglucobrassicin were isolated from roots [19].…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial activity of Capparis spinosa as its usages in traditional medicine

Mahboubi¹,

Mahboubi

2014

Herba Polonica

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S u m m a r yCapparis spinosa roots and fruits are traditionally used for the treatment of diseases such as diarrhea and hemorrhoids. In the 10 th century, farmers also used aqueous extract from its roots for disinfecting their plants' seeds. Due to widespread use of this plant in traditional medicine, we evaluated different extracts (aqueous, methanol, ethanol and ethyl acetate) of fruits and roots of this plant against bacteria and fungi causing infections in plants or humans. The total phenolic and flavonoid content of extracts from fruits and roots and the antioxidant activity were evaluated. The antimicrobial activity was evaluated by microdilution assay in fluid medium. Among different extracts from roots and fruits, root ethyl acetate and fruit methanol extracts had higher total phenolic content, while fruit ethyl acetate extract contained higher total flavonoid content. The higher antioxidant activity was shown for roots ethanol extract (IC 50 =88 µg/ml). As its traditional uses, roots aqueous extract from C . spinosa exhibited inhibitory effect against bacteria and fungi with the exception of Pseudomonas aeruginosa. With the exception of fruit aqueous extract, other extracts (methanol, ethanol and ethyl acetate) from fruit and root exhibited good activity against microorganisms, especially fungi. This study reveals the traditional uses of roots and fruit extracts as antimicrobials agent.

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“…In China, C. spinosa has been used since ancient times in traditional medicine especially for the treatment of rheumatism and gout (Fu et al, 2008). With regard to the constituents of the C. spinosa, a number of flavonoids, alkaloids, terpenoids, volatile oils and fatty acids have been reported (Matthäus & Ozcan, 2002;Sharaf et al, 1997;Khanfar et al, 2003;Yang et al, 2008).…”

Section: Introductionmentioning

confidence: 99%