The characterisation of structural and antioxidant properties of isoflavone metal chelates

Dowling, Stephen; Regan, Fiona; Hughes, Helen

doi:10.1016/j.jinorgbio.2010.06.007

Cited by 70 publications

(61 citation statements)

References 36 publications

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“…In the present study, flavonols, flavones and isoflavones showed several bands in the ranges described )). However, bands in this region were not reported previously in the literature [16,45]. This region cannot be considered to characterize genistein compound.…”

mentioning

confidence: 68%

“…Similarly, Pei et al used MIR spectroscopy to analyze Herba epimedii (traditional Chinese medicine); the correlation value, representing the similarity of two spectra of an herbal sample and the standard phenolic substance, icariin (flavonol glycoside), in the 1280-1200 cm À1 region, has been found to be a good indicator for fast and effective quality control and could be used as a screening criterion for the herbs [15]. MIR spectroscopy was also used in the framework of a study on the chelation of isoflavones like biochanin A (Omethylated isoflavone) and genistein (isoflavone) with metal [16]. In the same period, the technique was used by Gorinstein et al to determine the bioactivity of exotic fruits [17].…”

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confidence: 99%

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Phenolic compound explorer: A mid-infrared spectroscopy database

Abbas

Compère

Larondelle

et al. 2017

Vibrational Spectroscopy

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confidence: 68%

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confidence: 99%

Phenolic compound explorer: A mid-infrared spectroscopy database

Abbas

Compère

Larondelle

et al. 2017

Vibrational Spectroscopy

100

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“…It has been reported that the free-radical scavenging ability of quercetin is highly directed toward hydroxyl radical (OHC). The value of the hydroxyl inhibition rate of the Qu-GeNPs was close to a known antioxidant, such as ascorbic acid, [46] which inhibited hydroxyl oxidation by 45 % (50 mm). As shown in Figure 7, the inhibitory effect of the Qu and Qu-GeNPs on OHC was concentration-related, and the suppression ratio increased as the sample concentration increased in the range of 20- Figure 7 shows that when the concentration of Qu-GeNPs was 200 mm, the scavenging rate of hydroxyl radicals reached 89 %, which was significantly higher than that of Qu (49 %) at the same concentration.…”

Section: Ph-mediated Drug Release Of Qu In Vitromentioning

confidence: 61%

Facile Synthesis of Multifunctional Germanium Nanoparticles as a Carrier of Quercetin to Achieve Enhanced Biological Activity

Guo

Yang

Zhang

et al. 2014

Chemistry An Asian Journal

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A simple method for preparing quercetin surface-functionalized germanium nanoparticles (Qu-GeNPs) with enhanced antioxidant and anticancer activity is reported. Spherical germanium nanoparticles (GeNPs) were capped by quercetin (Qu) with a mean particle size of approximately 33 nm and were characterized by TEM, AFM, UV-visible absorption spectroscopy, FTIR, and XRD measurements. The in vitro drug release of Qu from the Qu-GeNPs indicated that Qu could principally be distributed around tumor tissues rather than in the normal section and Qu-GeNPs were internalized by MCF-7 cells. Their biological activity test results indicated that these Qu-GeNPs possessed stronger hydroxyl-scavenging effects and proliferative inhibition effect on MCF-7 cancer cells than quercetin, thus suggesting that the strategy to use GeNPs as a carrier of Qu could be an efficient way to achieve enhanced antioxidant and anticancer activity. In addition, Qu-GeNPs possessed a high apoptotic induction effect in cancer cells, especially in high dosages, and could arrest MCF-7 cells in the S phase.

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“…Therefore, Chry-Ge complex showed higher suppression effect toward DPPH radicals than that of free Chry, indicating higher scavenging effect of Chry-Ge complex toward DPPH radical. The value of DPPH inhibition rate of the Chry-Ge complex was close to a known antioxidant, such as ascorbic acid, 24 which inhibited DPPH oxidation by 45% 50 lM. This are mainly attributed to synergetic effects of ChryGe complex.…”

Section: Introductionmentioning

confidence: 58%