The Characterisation of Crystalline and Amorphous Aloin

Lister, Ryan; Pride, R. R. A.

doi:10.1111/j.2042-7158.1959.tb10445.x

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Aloes1

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1963

1991

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Cited by 4 publications

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“…As this is a C-glycoside there are obvious difficulties in devising a suitable bioassay. Lister and Pride (1959) used the consistency of rat faecal pellets as a measure of laxative activity, as recommended by Latvan et al (1952), but large doses of the dnig were required to produce an effect. Mapp and McCarthy (1970) also used rats but again found they required quite high doses.…”

Section: Aloesmentioning

confidence: 99%

Biological Assay and Its Relation to Chemical Structure

Jw¹

1976

Pharmacology

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Section: Aloesmentioning

confidence: 99%

Biological Assay and Its Relation to Chemical Structure

Jw¹

1976

Pharmacology

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Aloe barbadensis Mill. (= A. vera L.)

Cavallini

Natali

Sánchez

1991

Biotechnology in Agriculture and Forestry

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The compounds in Aloë leaf exudates: a review

Reynolds

1985

Botanical Journal of the Linnean Society

110

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The drug Bitter Aloes has been used for several thousands of years because of its purgative properties and later several species of the plant have been cultivated for horticultural interest. In addition, many more local therapeutic properties have been recorded. Research has been largely directed towards the physiologically active components during the 50s and 60s. Extensions to this work in the last decade have been made in Germany, Japan and South Africa. Compounds have been characterized from the dried exudate prepared for drug purposes and from a few species. A number of anthraquinones have been recognized both in the free state and as glycosides. Other compounds with phenolic groups include chromones and a phenyl‐pyranone. Chromatographic methods have been developed for recognizing some of these compounds and estimating the levels of those of pharmacological interest. Distribution of some of the compounds among a number of species is described showing that among some groups it has taxonomic significance. The biology of secretion and exudation from Aloë leaves remains largely unknown although fragmentary evidence points to interesting and potentially useful activity in some of the components.

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The Characterisation of Crystalline and Amorphous Aloin

Abstract: Tests are described showing the differences between amorphous aloin and that of the B.P. 1953. One of these tests might, with advantage, be incorporated in official publications to differentiate crystalline aloin from the relatively impure and less active amorphous aloin.

Cited by 4 publications

References 4 publications

Biological Assay and Its Relation to Chemical Structure

Biological Assay and Its Relation to Chemical Structure

Aloe barbadensis Mill. (= A. vera L.)

The compounds in Aloë leaf exudates: a review

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