The changing pattern of bacterial meningitis in adult patients at a large tertiary university hospital in Barcelona, Spain (1982–2010)

Listeria monocytogenes meningitis in the elderly: Distinctive characteristics of the clinical and laboratory presentation

“…Elderly patients are considered at the highest risk of an unfavourable outcome after bacterial meningitis, but prior to our study, there were no data on the differences in outcome in relation to aetiology. 1,9 The observation by Krone that ageing patients have a poor outcome after pneumococcal infection because of a decreased ability to control the infection or a deregulated cytokine response supports the findings of our analysis and warrants early intensive care when pneumococcal meningitis is diagnosed. 10 In conclusion, our study highlighted that bacterial meningitis must be considered in elderly patients presenting with febrile coma, even when neck stiffness is absent.…”

“…1 In ageing people, infections are not only more frequent compared to the younger population, but they also have a distinct epidemiological and clinical presentation, treatment and outcome. 2 The aim of this prospective observational study was to evaluate, in patients aged over 50 years consecutively observed during a ten-year period at the 'D.…”

The microbiology and clinical characteristics of bacterial and fungal meningitis in a Chinese hospital

“…In our current study, we investigated the differences in the initial clinical and laboratory findings between patients associated with CNS, Ab and CN. Multiple studies have shown that headache, fever and neck stiffness were common signs and symptoms in patients with bacterial meningitis [1,18,[49][50][51]. Our study also showed that fever and meningeal irritation signs were common symptoms in the three groups.…”

Characteristics and outcome of spontaneous bacterial meningitis in patients with cancer compared to patients without cancer

“…The characteristics of this cohort have been described previously. [4,8,12] From 1999, information about the results of cerebral computed tomography (CT) scans, diagnostic sequence of CT in relation to lumbar puncture (LP), and start of antibiotic treatment were also registered.…”

“…We observed in previous studies that adults with BM had underlying malignancies in 15% of cases; furthermore there was a higher frequency in more recent years (8% during the period 1982–1995; 21% during 1996–2010) and among older patients (11% in the nonelderly; 19% in ≥65 years). [4,8] …”