The changing face of complicated infantile hemangioma treatment

Menapace, Deanna C.; Mitkov, Mario; Towbin, Richard B.; Hogeling, Marcia

doi:10.1007/s00247-016-3643-6

Cited by 32 publications

(27 citation statements)

References 113 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Complicated lesions are best managed in a multidisciplinary fashion. 12 For children with infantile hemangioma who fail to respond or have an incomplete response to medical therapy, surgical resection may be a relatively safe treatment alternative. Children older than 3 years of age with hemangiomas had less surgical adverse events than younger children.…”

Section: Pediatric Dermatologymentioning

confidence: 99%

Outcomes of surgical treatment for hemangiomas

Cheng

Liu

Lee

2019

Pediatric Dermatology

View full text Add to dashboard Cite

Objective To quantify complications and rates of adverse events associated with surgical excision of hemangiomas in children using a national surgical database. Data source Pediatric American College of Surgeons (ACS) National Surgical Quality Improvement Program® (ACS NSQIP®‐pediatric), years 2012‐2016. Methods Subjects included children under 18 years with a postoperative diagnosis of International Classification of Diseases (ICD), 9th revision code: 228.00 and 228.01, or ICD 10 codes D18.00 and D18.01—hemangioma, any site and hemangioma, of skin and subcutaneous tissue. Results A total of 1180 patients were included. The median age was 3.2 years (interquartile range [IQR] 1.2 to 6.4 years old). No occurrences of deep incisional surgical site infection, nerve injury, mortality, sepsis, septic shock, or blood stream infections were noted. In multivariate analysis, age ≤ 3 years and advanced American Society of Anesthesiologists class were significant predictors of adverse events (P = 0.035 and 0.001, respectively). Conclusions For children with infantile hemangioma who fail to respond or have an incomplete response to medical therapy, surgical resection may be a relatively safe treatment alternative. Children older than 3 years of age with hemangiomas had less surgical adverse events than younger children. Overall, however, the surgical complications rates were low and deemed relatively minor.

show abstract

Section: Pediatric Dermatologymentioning

confidence: 99%

Outcomes of surgical treatment for hemangiomas

Cheng

Liu

Lee

2019

Pediatric Dermatology

View full text Add to dashboard Cite

show abstract

“…Shamir et al months of life (62). Noninvoluting congenital hemangioma does not regress but may grow in proportion to the child (54). CHH manifests in the newborn period as an abdominal mass.…”

Section: State Of the Art: Hepatic Imaging In Neonates And Young Infantsmentioning

confidence: 99%

“…Lack of elevated AFP helps differentiate these calcifying lesions from hepatoblastoma. In cases with arteriovenous shunt, seen more often in CHH than IHH, there is enlargement and increased flow velocity of surrounding hepatic arteries and veins, with flow voids in or around the lesion, and tapering of the aorta distal to celiac trunk (54,63,65).…”

Section: Imaging Of Hemangiomamentioning

confidence: 99%

“…CHHs, unlike IHHs, may be identified prenatally, are fully formed at the time of birth, and typically manifest as a solitary large mass. Three patterns of growth have been recognized: rapidly involuting, noninvoluting, and partially involuting (54). Involution of rapidly involuting congenital hemangioma begins soon after birth and is complete by 14 (IHH) and congenital hepatic hemangioma (CHH).…”

Section: Congenital Hepatic Hemangiomamentioning

confidence: 99%

“…Many authors have restricted the term hemangioendothelioma specifically to epitheliod hemangioendothelioma, an entity distinct from IHH and CHH. The term hemangioendotheliomatosis, which was previously used for multiple hypervascular liver lesions, has been supplanted by multifocal or diffuse IHH (53,54). There is substantial overlap in imaging of these tumors.…”

Section: Congenital Hepatic Hemangiomamentioning

confidence: 99%

See 2 more Smart Citations

Hepatic Imaging in Neonates and Young Infants: State of the Art

et al. 2017

View full text Add to dashboard Cite

Neonatal liver disease is an important source of morbidity in the pediatric population. The manifestation of liver disease in young infants may be different than in older patients, and there are a number of diagnoses that are unique to this age group. Familiarity with these entities is important as imaging plays a key role in the diagnostic workup, and prompt diagnosis is necessary to prevent complications. This article reviews the spectrum of liver pathologies that can manifest in the first 6 months of life and is intended to educate the general radiologist who may be faced with interpretation of neonatal liver imaging. Categories of disease that will be reviewed include cholestatic diseases, tumors, vascular anomalies, and acquired diseases. The authors will also review optimization of ultrasonography (US) and magnetic resonance imaging of the liver and present a systematic method for interpretation of neonatal liver US findings in the context of clinical and laboratory findings. RSNA, 2017.

show abstract