The changing epidemiology of liver diseases in Asia

Sun, Jian; Tanaka, Junko; Valenti, Luca

doi:10.1111/liv.15354

Liver International

2022

DOI: 10.1111/liv.15354

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The changing epidemiology of liver diseases in Asia

Jian Sun

Junko Tanaka

Luca Valenti

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Cited by 2 publications

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“…(1.8%) were affected by chronic liver disease and cirrhosis. It is estimated that approximately 7% to 20% of non-obese Asians with a body mass index (BMI) below 25 kg/m 2 have non-alcoholic fatty liver disease (NAFLD) [2].…”

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confidence: 99%

Hepatoprotective Effects of Liv.52 in Chronic Liver Disease Preclinical, Clinical, and Safety Evidence: A Review

Kantharia,

Kumar,

Jain

et al. 2023

Gastroenterology Insights

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Chronic liver disease (CLD) is a growing concern worldwide. The common etiological factors include infection, alcohol abuse, exposure to hepatotoxic drugs, autoimmune disorders, and metabolic diseases. The chronic liver disease progresses to liver cirrhosis and its consequent complications. It is routinely managed by a combination of various therapies in combination with lifestyle modifications. The current literature supports the growing importance of the usage of herbal medicines in the management of CLD due to their efficacy and very low incidence of adverse effects. Liv.52 is a known polyherbal formulation and has been used for over 50 years in India and other countries. The evidence collected from preclinical and clinical studies supports the use of Liv.52 in symptomatic improvement and supportive treatment due to hepatitis (including Hepatitis B), alcoholic liver disease, non-alcoholic fatty liver disease (NAFLD), and non-alcoholic steatohepatitis (NASH) and hepatotoxicity due to drugs used in the treatment of tuberculosis. Liv.52 has also shown some preliminary hepatoprotective effects in patients with liver cirrhosis due to its potential antioxidant and anti-inflammatory effects. Both the syrup and tablet formulations are well tolerated and have shown a good safety profile. Liv.52 may be a favorable herbal choice for the management of CLD due to various etiologies.

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confidence: 99%

Hepatoprotective Effects of Liv.52 in Chronic Liver Disease Preclinical, Clinical, and Safety Evidence: A Review

Kantharia,

Kumar,

Jain

et al. 2023

Gastroenterology Insights

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show abstract

Worldwide Increasing Prevalence of Non-alcoholic Steatohepatitis as an Indication of Liver Transplantation: Epidemiological View and Implications

Ferretti,

Barreyro

2024

Curr Hepatology Rep

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The changing epidemiology of liver diseases in Asia

Cited by 2 publications

References 18 publications

Hepatoprotective Effects of Liv.52 in Chronic Liver Disease Preclinical, Clinical, and Safety Evidence: A Review

Hepatoprotective Effects of Liv.52 in Chronic Liver Disease Preclinical, Clinical, and Safety Evidence: A Review

Worldwide Increasing Prevalence of Non-alcoholic Steatohepatitis as an Indication of Liver Transplantation: Epidemiological View and Implications

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