The Changing Epidemiology of Human Brucellosis in Texas, 1977–1986

Taylor, Jeffery P.; Perdue, J.

doi:10.1093/oxfordjournals.aje.a115308

Cited by 52 publications

(34 citation statements)

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“…This could have reduced the chances of Kuwaiti females taking care of the cattle. Brucellosis traditionally affects young to middle-aged individuals [17,18]. Our results confirm this, as two thirds of confirmed cases in this study were in the age group of 20-45 years.…”

Section: Discussionsupporting

confidence: 90%

Seroepidemiological and Microbiological Study of Brucellosis in Kuwait

Ts¹,

Panigrahi

Emara³

et al. 2004

Med Princ Pract

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Objective: The primary objective of the study was to determine the prevalence of brucellosis and the antimicrobial susceptibility pattern of local Brucellae isolates in the Infectious Diseases Hospital, Kuwait. Subjects and Methods: A single serum sample was collected from each of 1,836 patients of different nationalities from January 2000 to December 2001. Any patient with a provisional diagnosis of fever or brucellosis had a standard tube agglutination (STA) test for the quantitation of Brucella antibodies. Blood cultures were done in 166 of 455 patients with significant STA titers, using the Bactec system. Antimicrobial susceptibility testing of 123 isolates of Brucella spp. was done against 8 antimicrobial agents. Results: A total of 455 serum samples (24.8%) having an STA titer of ≧1:160 were presumptively diagnosed as cases of brucellosis. The peak isolation was in April and May. Brucella spp. were isolated from 123 blood cultures (74.1%). The blood culture isolation rate was significantly higher in patients with an STA titer of ≧1:1,280 than in those with an STA titer of ≤1:160 (p < 0.05). Antimicrobial susceptibility testing showed good in vitro activity of tetracycline, gentamicin, amikacin, streptomycin and ciprofloxacin against all isolates. Azithromycin had good anti-Brucella activity against only 42% of the isolates, while rifampicin and trimethoprim-sulfamethoxazole showed low in vitro anti-Brucella activity against 8 and 25% of the isolates, respectively. Conclusion: Brucellosis is quite common in Kuwait. Kuwaiti and Bangladeshi nationals were most affected. Significant titers on the STA test were detected in 24.8% of serum samples. Good in vitro activity against all isolates was found with tetracycline, gentamicin, amikacin, ciprofloxacin and streptomycin, and low activity with azithromycin, rifampicin and trimethoprim-sulfamethoxazole.

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Section: Discussionsupporting

confidence: 90%

Seroepidemiological and Microbiological Study of Brucellosis in Kuwait

Ts¹,

Panigrahi

Emara³

et al. 2004

Med Princ Pract

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“…This was attributed to the disease not having been eradicated from the animals yet and the ongoing consumption of un-pasteurized milk and dairy products even in urban areas. Even though there are studies showing that occupational brucellosis is more common in males (8), some other studies report that males and females are affected equally (3, 9, 10). We found, in agreement with these results, that the distribution of the disease was equal in both sexes (about 51.5% of the cases were females).…”

Section: Discussionmentioning

confidence: 99%

Osteoarticular Involvement among 202 Brucellosis Cases Identified in Central Anatolia Region of Turkey

et al. 2011

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Objective The musculoskeletal system is one of the most commonly affected systems in brucellosis. The objective of this study was to determine the frequency, types, and clinical features of osteoarticular involvement among cases with brucellosis in the Central Anatolia region of Turkey and to establish the differences between patients with and without osteoarticular involvement. Methods Included in this study were 202 patients with Brucellosis presented between June 2003 and June 2009. The diagnosis of osteoarticular system complications was established by physical examination and radiological findings obtained by diagnostic imaging tools. Magnetic resonance images of thoracic, lumbar or sacral vertebrae were acquired from patients with back pain, low back pain and sacro-iliac joint pain. Results Osteoarticular involvement was noted in 94 patients (46.5%). The most common sources of infection are employment in farming and/or consumption of un-pasteurized milk or dairy products, especially fresh cheese in 53 (75.7%) cases. The mean age is 46.7±18 years. Sacroiliitis is the most frequent osteoarticular involvement (60.6%), 82.4% of which is bilateral. Sacroiliitis was followed by spondylodiscitis in 36 (38.3%), peripheral arthritis in 15 (16%), bursitis in 1(1.1%) case. Patients with osteoarticular involvement received medical treatment for at least three months. Conclusion The ratio and anatomical region of osteoarticular involvement in brucellosis show variability among countries. In this study, it is demonstrated that sacroiliitis is the most common form of osteoarticular involvement in the Central Anatolia region of Turkey. In endemic countries such as Turkey, this disease should be included in the differential diagnosis for patients with symptoms of sacroiliitis, spondylodiscitis or those with articular pain.

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“…The combination of doxycycline and streptomycin maybe the most effective and least toxic (15,16). Although the incidence of brucellosis had markedly decreased in developed countries as mentioned by recent reports (12,15,17), it should be recalled that Brucella spp. could be imported from endemic areas.…”

Section: Discussionmentioning

confidence: 99%

An Unusual Case of Brucellosis in Japan: Difficulties in the Differential Diagnosis from Pulmonary Tuberculosis.

et al. 1996

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Humanbrucellosis is an imported zoonosis extremely uncommonin Japan. Brucellosis was found in a 38-year-old surgeon who had never been abroad; he developed intrapulmonary infiltrates and pleural thickening indistinguishable from pulmonary tuberculosis. Despite extensive antibiotic therapy for tuberculosis he developed systemic serositis. A culture of resected lung tissues grew CO2-required coccobacilli. Polymerase chain reaction test using a specific primer pair for Brucella abortus revealed that the isolated pathogen is highly homologous to B. abortus. We emphasize that undetermined cases of humanbrucellosis maybe present in Japan.

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The Changing Epidemiology of Human Brucellosis in Texas, 1977–1986

Cited by 52 publications

References 0 publications

Seroepidemiological and Microbiological Study of Brucellosis in Kuwait

Seroepidemiological and Microbiological Study of Brucellosis in Kuwait

Osteoarticular Involvement among 202 Brucellosis Cases Identified in Central Anatolia Region of Turkey

An Unusual Case of Brucellosis in Japan: Difficulties in the Differential Diagnosis from Pulmonary Tuberculosis.

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