The Challenge of Protocols for Reflux Disease: A Review and Development of a Critical Pathway

Altman, Kenneth W.; Prufer, Neil; Vaezi, Michael F.

doi:10.1002/lary.22264

Cited by 9 publications

(23 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As previously discussed, significant variability regarding the type of medication use is also noted among PCPs and otolaryngologists. [4][5][6][7]22 Thus, further study is needed to examine the practice patterns related to specific medication trials between and within these treating specialties to uncover areas for improved care.…”

Section: Discussionmentioning

confidence: 99%

Assessing factors related to the pharmacologic management of laryngeal diseases and disorders

2013

View full text Add to dashboard Cite

Objective To examine how age, gender, comorbidity, geography, provider type, and laryngeal pathology influence the use of pharmacological treatment in managing patients with laryngeal disorders. Study Design Retrospective analysis of data from a large, nationally representative administrative U.S. claims database. Methods Patients with a laryngeal disorder based on ICD-9-CM codes from January 1, 2004 to December 31, 2008, seen as an outpatient by a primary care physician (PCP), otolaryngologist, or both, and continuously enrolled for 12 months were included. Data regarding pharmacy claims, age, gender, geographic location, comorbid conditions, provider type, and laryngeal diagnosis were collected. To identify factors that influenced whether a patient received a medication or not, a logistic regression was performed. Results Of almost 55 million individuals in the database, 258,705 had a laryngeal diagnosis, 12 months post-index date follow-up, and an outpatient encounter with a PCP, otolaryngologist, or both. 135,973 (52.6%) unique patients, mean age 47.4 years (22.2 SD) with 61.9% female, received a medication, and 122,732 (47.4%), mean age 47.4 (19.8 SD) with 65.8% female, did not. Higher odds ratios (ORs) for medication treatment were associated with PCPs versus otolaryngologists, acute laryngitis, the south region, and patients with comorbid conditions. Variable prescription patterns were also observed for age and gender. Conclusion Multiple factors are associated with the use of medical treatment for laryngeal disorders.

show abstract

Section: Discussionmentioning

confidence: 99%

Assessing factors related to the pharmacologic management of laryngeal diseases and disorders

2013

View full text Add to dashboard Cite

show abstract

“…(1) Patients already taking PPIs or who have PPIs initiated should be followed and doses reduced to the minimum effective dose based on symptom improvement. 25,30 If patients cannot reduce their PPI doses, objective reflux testing can examine the correlation between reflux events and patient symptoms and may lead to consideration of alternative diagnoses and treatments. 24 (2) Providers should have discussions with patients about specific PPI-weaning protocols to help reduce rebound reflux symptoms when the dose is tapered and thus the resulting persistent dependence on PPIs.…”

Section: Discussionmentioning

confidence: 99%

Associations between Community‐Acquired Pneumonia and Proton Pump Inhibitors in the Laryngeal/Voice‐Disordered Population

Lee

Leiman

Roy

et al. 2018

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

Objectives: To examine the relationship between community acquired pneumonia (CAP) and proton pump inhibitor (PPI) treatment in laryngeal/voice disordered patients. Study Design: Retrospective cohort analysis. Setting: Large, national administrative U.S. claims database. Subjects and Methods: Patients ≥ 18 years of age with outpatient treatment for a laryngeal/voice disorder per ICD-9-CM codes from January 1, 2010 to December 31, 2014 with 12 months continuous enrollment prior to the index date (first laryngeal/voice disorder diagnosis), no pre-index diagnosis of CAP, and had prescription claims captured from 1 year pre-index to end of follow-up were included. Patient demographics, comorbid conditions, index laryngeal diagnosis, number of unique pre-index patient encounters, and CAP diagnoses during 3 year post-index date were collected. Two models, a time-dependent Cox regression model and a propensity score based approach with marginal structural model, were each separately performed in patients with and without pre-index date PPI prescriptions. Results: 392,355 unique patients met inclusion criteria. 188,128 (47.9%) patients had a PPI prescription. The 3 year absolute risk for CAP was 4.0% and 5.3% in patients without and with pre-index PPI use, respectively. The CAP occurrence for a person who already received a PPI is 30% to 50% higher than for a person who has not yet had a PPI but may receive one later for patients without and with pre-index date PPI use, respectively. Conclusions: Patients without and with pre-index date PPI use experienced roughly 30% to 50% increased likelihood of CAP, respectively, compared to patients who had not had PPI prescriptions.

show abstract

“…Studies have found the prevalence of GERD to increase almost every year and in the study which was conducted by El‐Serag et al, 13 such prevalence was found to increase by 4% every year since 1976. Similarly, Altman et al found a significant increase in hospital visits due to similar complaints and such increase has been found to account for the majority of cases of dysphonia 5,9 …”

Section: Introductionmentioning

confidence: 87%

Utility of reflux finding score and reflux symptom index in diagnosis of laryngopharyngeal reflux disease

Abraham

Kahinga

2022

Laryngoscope Investig Oto

View full text Add to dashboard Cite

Objective The study aimed to determine the utility of reflux finding score (RFS) and reflux symptom index (RSI) in the diagnosis of laryngopharyngeal reflux disease (LPRD) in Dar es Salaam, Tanzania. Methods A prospective hospital‐based cross‐sectional study was conducted at a private hospital in Dar es Salaam, Tanzania. Data were analyzed using Statistical Package for Social Sciences version 21. Relationship between independent and dependent variables was established using chi‐square test, a variable with p‐value of equal or less than 0.05 was considered to be statistically significant. Results In this study, a total of 2500 patients were recruited, out of which 800 (32.0%) were males and 1700 (68.0%) were female. Out of the 2500, 1520 (60.8%) patients were found to have a RSI of >13. Out of the 1520 patients subjected to 70‐degree laryngoscopy, 1425 patients (95.0%) were found to have a RFS > 7. Of the 1425 patients with RFS > 7, 260 were males (18.2%) and 1165 were females (81.8%). Conclusion RFS and RSI have demonstrated their role in establishing the diagnosis of LPRD. Level of Evidence 4

show abstract

The Challenge of Protocols for Reflux Disease: A Review and Development of a Critical Pathway

Cited by 9 publications

References 0 publications

Assessing factors related to the pharmacologic management of laryngeal diseases and disorders

Assessing factors related to the pharmacologic management of laryngeal diseases and disorders

Associations between Community‐Acquired Pneumonia and Proton Pump Inhibitors in the Laryngeal/Voice‐Disordered Population

Utility of reflux finding score and reflux symptom index in diagnosis of laryngopharyngeal reflux disease

Contact Info

Product

Resources

About