The Challenge of E-Spinning Sub-Millimeter Tubular Scaffolds—A Design-of-Experiments Study for Fiber Yield Improvement
Cilia A. Sandhoff,
Alexander Loewen,
Yasmin Kuhn
et al.
Abstract:In tissue engineering, electrospinning has gained significant interest due to its highly porous structure with an excellent surface area to volume ratio and fiber diameters that can mimic the structure of the extracellular matrix. Bioactive substances such as growth factors and drugs are easily integrated. In many applications, there is an important need for small tubular structures (I.D. < 1 mm). However, fabricating sub-millimeter structures is challenging as it reduces the collector area and increases th… Show more
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