2006
DOI: 10.1016/j.jaci.2005.12.511
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The Cerebral Processing of Itch - An Investigation with Functional Magnetic Resonance Tomography

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“…Nevertheless, some data is available on the neurobiology of skin picking, [9,82,96] and there is also a growing literature on the neurobiology of itching and scratching. [97][98][99] Evidence that pharmacotherapy can be effective is consistent with underlying disturbance.…”
Section: Skin Picking Disordermentioning
confidence: 98%
“…Nevertheless, some data is available on the neurobiology of skin picking, [9,82,96] and there is also a growing literature on the neurobiology of itching and scratching. [97][98][99] Evidence that pharmacotherapy can be effective is consistent with underlying disturbance.…”
Section: Skin Picking Disordermentioning
confidence: 98%
“…)。抓搔症的核心特征在于"不可控" (Jentsch & Taylor, 1999) (Keuthen, Koran, Aboujaoude, Large, & Serpe, 2010)。另一项对美国社区样本(n = 354)进行的调查发 现,皮肤抓搔障碍的患病率是 5.4% (Hayes, Storch, & Berlanga, 2009)。 抓搔症不仅具有高患病率,而且与其他精神疾病 具有高共病率。如果病情严重,甚至可能导致患者死 亡。这使得抓搔症成为一个值得关注的公共健康问题 (Arnold, Auchenbach, & McElroy, 2001;Flessner & Woods, 2006;Grant & Odlaug, 2009;Wilhelm et al, 1999)。近期,抓搔症首次写入美国精神疾病诊断和统 计手册第五版(Diagnostic and Statistical Manual of (Stein et al, 2010) (Arnold et al, 1998)。也有报告指出,在 40 例抓搔症 患者中,10 岁之前儿童就占 47.5% )。 抓搔症的诊断与干预 抓搔症更常见于女性 (Arnold et al, 1998;Keuthen et al, 2000;Odlaug & Grant, 2008) (Aron, Fletcher, Bullmore, Sahakian, & Robbins, 2003)。 虽然学界对瘙痒和抓挠的神经生物学研究越来 越多 (Darsow et al, 2006, Leknes et al, 2007Yosipovitch et al, 2008;Cullen et al, 2001;Frecska & Arato, 2002;Grant & Odlaug, 2009),但人们对抓搔症的神经 生物学基础的认识仍然非常有限。目前还没有关于抓 搔症的神经影像学研究。 6. 抓搔症的药物治疗与行为干预 抓搔症患者常常因自己的行为而感到尴尬和羞 愧 (Grant, Odlaug, & Kim, 2007;Wilhelm et al, 1999),…”
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