With the development of smart distribution networks, the access of distribution generation (DG) presented new challenges to the operation and protection of power systems. Based on the hierarchical and modular structural ideas, this paper constructs a centralized distribution network protection system structure with a split layered architecture. The system improves protection accuracy and reliability through split protection, and achieves independent configuration, flexibility, fault isolation, information exchange and scalability. At the same time, protection efficiency is improved through hierarchical protection, hierarchical configuration, coordinated operation and rapid recovery are achieved to optimize power supply reliability. Under different fault scenarios, split and layered distribution network centralized protection is used to analyze the interaction process of random loads and intermittent distributed power sources on the active distribution network. Simulation results show that the architecture is effective and correct.